ArticleJournal of medical case reports2021
Clinical course of choroidal neovascular membrane in West Nile virus chorioretinitis: a case report.
Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- [From Bite to Loss of Vision-Ocular Complications of West Nile Virus].Die Ophthalmologie · 2026Article
- Atypical Unilateral Multifocal Choroiditis and Retinal Vasculitis Following Presumed West Nile Virus Infection.Ocular immunology and inflammation · 2025Article
- West Nile Virus Chorioretinitis: First Case with Ocular Involvement in Türkiye.Turkish journal of ophthalmology · 2025Article
- Diagnostic Challenges in Inflammatory Choroidal Neovascularization.Medicina (Kaunas, Lithuania) · 2024Review
- Encephalitic Arboviruses of Africa: Emergence, Clinical Presentation and Neuropathogenesis.Frontiers in immunology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis report describes the clinical course of choroidal neovascular membrane (CNV) in West Nile virus-associated chorioretinitis. CASE PRESENTATION: A 28-year-old Italian woman was referred to our institution because of reduced visual acuity in the left eye dating back 4 months. A diagnosis of retinal vasculitis in the right eye and chorioretinitis with CNV in the left eye was made. A complete workup for uveitis revealed positivity only for anti-West Nile virus immunoglobulin M (IgM), while immunoglobulin G (IgG) was negative. Whole-body computed tomography and nuclear magnetic resonance imaging of the brain were also negative. Therefore, the patient was treated with a combination of oral prednisone (starting dose 1 mg/kg per day) and three intravitreal injections of bevacizumab 1.25 mg/0.05 ml, 1 month apart. Fourteen days from starting corticosteroid therapy and after the first intravitreal injection, the patient experienced increased visual acuity to 0.4. Response to therapy was monitored by clinical examination, ocular coherence tomography (OCT), OCT angiography and retinal fluorescein angiography. Three months later, resolution of CNV in the left eye was achieved and no signs of retinal vasculitis were detected in the right eye, while serum IgM for West Nile virus turned negative and IgG positive.
conclusionCNV may be a complication of West Nile virus-associated chorioretinitis, and only subclinical retinal vasculitis may also be found even in non-endemic regions.
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