ArticleWorld journal of surgical oncology2021
Effect of sidedness on survival among patients with early-stage colon cancer: a SEER-based propensity score matching analysis.
Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Prognosis in stage II colorectal cancer: the effect of the primary tumor location and biomarkers-a retrospective cohort study.The oncologist · 2025Article
- Impact of Sidedness of Colon Cancer on Epidemiological, Clinical Presentation, Surgical, Pathological, and Oncologic Outcomes.Journal of personalized medicine · 2024Article
- Response to Comment on: "Prognostic Relevance of Primary Tumor Sidedness in Early-Stage Colorectal Cancer: An Integrated Analysis of 4 Randomized Controlled Trials (JCOG2003A)".Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Primary Tumor Sidedness Associated with Clinical Characteristics and Postoperative Outcomes in Colon Cancer Patients: A Propensity Score Matching Analysis.Journal of clinical medicine · 2024Article
- Prognostic factors and survival disparities in right-sided versus left-sided colon cancer.Scientific reports · 2024Article
- Sidedness is not a prognostic factor in an unselected cohort of patients with colon cancer but prognosis for caecal carcinoma is worse - A multivariate analysis of a large single institution database.International journal of colorectal disease · 2024Article
- Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival.World journal of gastrointestinal oncology · 2022Article
- Development and validation of a new stage-specific nomogram model for predicting cancer-specific survival in patients in different stages of colon cancer: A SEER population-based study and external validation.Frontiers in oncology · 2022Article
- Effect of the duration of the capecitabine regimen following colon cancer surgery in an elderly population: a retrospective cohort study.World journal of surgical oncology · 2021Article
- Safety and effectiveness evaluation of a two-handed technique combining harmonic scalpel and laparoscopic Peng's multifunction operative dissector in laparoscopic hemihepatectomy.World journal of surgical oncology · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost previous studies compared survival between left-sided and right-sided colon cancer without adjustment for clinicopathological parameters. We investigated the effect of sidedness on survival among patients with early-stage colon cancer, using a propensity score matching method.
methodsThe 18 registry custom data within the SEER database were used to identify patients who were diagnosed with colon cancer between 2010 and 2014. A propensity score matching analysis was performed using the nearest neighbor method. Survival was estimated using the Kaplan-Meier method. A Cox proportional hazards model was applied to determine the prognostic factors.
resultsIn the unmatched cohort, 25,094 (35.72%) patients were diagnosed with left-sided colon cancer and 45,156 (64.28%) with right-sided colon cancer. After propensity score matching, each cohort included 5118 patients, and the clinicopathological characteristics were well balanced. In the unmatched cohort, left-sided colon cancer had superior all-cause (χ
conclusionsAfter adjusting for clinicopathological characteristics in this study, sidedness showed no impact on survival in early-stage colon cancer. However, sidedness was associated with prognostic differences in stages II and III early-stage colon cancer.
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