Evidence map›Paper›PMID 33874798›Full record

ArticleSLAS technology2021

A Machine Vision Approach for Bioreactor Foam Sensing.

Jonas Austerjost, Robert Söldner, Christoffer Edlund, Johan Trygg, David Pollard, Rickard Sjögren

Abstract read
In one paragraph

Article in SLAS technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonas AusterjostSartorius Corporate Research, Sartorius Stedim Biotech GmbH, Göttingen, Germany.ORCID 0000-0002-2080-1556
Robert SöldnerSartorius Corporate Research, Sartorius Stedim Biotech GmbH, Göttingen, Germany.
Christoffer EdlundSartorius Corporate Research, Sartorius Stedim Data Analytics AB, Umea, Sweden.ORCID 0000-0003-0003-3681
Johan TryggSartorius Corporate Research, Sartorius Stedim Data Analytics AB, Umea, Sweden.
David PollardSartorius Corporate Research, Sartorius Stedim North America Inc., Boston, USA.
Rickard SjögrenSartorius Corporate Research, Sartorius Stedim Data Analytics AB, Umea, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine vision is a powerful technology that has become increasingly popular and accurate during the last decade due to rapid advances in the field of machine learning. The majority of machine vision applications are currently found in consumer electronics, automotive applications, and quality control, yet the potential for bioprocessing applications is tremendous. For instance, detecting and controlling foam emergence is important for all upstream bioprocesses, but the lack of robust foam sensing often leads to batch failures from foam-outs or overaddition of antifoam agents. Here, we report a new low-cost, flexible, and reliable foam sensor concept for bioreactor applications. The concept applies convolutional neural networks (CNNs), a state-of-the-art machine learning system for image processing. The implemented method shows high accuracy for both binary foam detection (foam/no foam) and fine-grained classification of foam levels.

Indexed as

Machine LearningNeural Networks, ComputerAlgorithmsBioreactorsImage Processing, Computer-Assistedbioprocessingdeep learningfoam sensormachine visionprocess analytical technology

Identifiers

PMID33874798
PMCPMC8293757

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.