Evidence map›Paper›PMID 33874781›Full record

ReviewASN neuro

Rodent Models to Analyze the Glioma Microenvironment.

Susann Hetze, Ulrich Sure, Manfred Schedlowski, Martin Hadamitzky, Lennart Barthel

Abstract readReview
In one paragraph

Review in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Zebrafish Models of Paediatric Brain Tumours.International journal of molecular sciences · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Susann HetzeDepartment of Neurosurgery, University Hospital of Essen, Essen, Germany.
Ulrich SureDepartment of Neurosurgery, University Hospital of Essen, Essen, Germany.
Manfred SchedlowskiInstitute of Medical Psychology and Behavioral Immunobiology, University Hospital of Essen, Essen, Germany.
Martin HadamitzkyInstitute of Medical Psychology and Behavioral Immunobiology, University Hospital of Essen, Essen, Germany.
Lennart BarthelDepartment of Neurosurgery, University Hospital of Essen, Essen, Germany.ORCID 0000-0002-0503-8628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models are still indispensable for understanding the basic principles of glioma development and invasion. Preclinical approaches aim to analyze the treatment efficacy of new drugs before translation into clinical trials is possible. Various animal disease models are available, but not every approach is useful for addressing specific questions. In recent years, it has become increasingly evident that the tumor microenvironment plays a key role in the nature of glioma. In addition to providing an overview, this review evaluates available rodent models in terms of usability for research on the glioma microenvironment.

Indexed as

Disease Models, AnimalAnimalsBrain NeoplasmsGenetic EngineeringGliomaHumansMiceNeoplastic Stem CellsRatsRodentiaTumor MicroenvironmentXenograft Model Antitumor Assaysbrain tumorgliomapreclinical oncologyrodent modelsynthetic biologytumor microenvironment

Identifiers

PMID33874781
PMCPMC8060738

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.