ArticleThe New phytologist2003
Characterization of the Arabidopsis metallothionein gene family: tissue-specific expression and induction during senescence and in response to copper.
Article in The New phytologist, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 256 citations in OpenAlex.
- Single-nucleus RNA-seq and ATAC-seq analyses provide molecular insights into cadmium-stress response in alfalfa roots.Horticulture research · 2026Article
- Artificial selection for resistance to copper and off-target physiological and behavioral effects inbioRxiv : the preprint server for biology · 2025Article
- Functional analysis of root-preferential oil palm metallothionein promoter in tobacco.Transgenic research · 2024Article
- Decrypting Molecular Mechanisms Involved in Counteracting Copper and Nickel Toxicity in Jack Pine (Plants (Basel, Switzerland) · 2024Article
- Article
- Plants' molecular behavior to heavy metals: from criticality to toxicity.Frontiers in plant science · 2024Review
- Metallothionein family genes in kiwifruit: characterization and determining their roles in plant's response to different stresses.Frontiers in plant science · 2024Article
- Article
- Characterization of the Metallothionein Gene Family inAntioxidants (Basel, Switzerland) · 2023Article
- Evolution of Cd2+ and Cu+ binding in Helix pomatia metallothioneins.Metallomics : integrated biometal science · 2023Article
- Genome-wide analysis of the metallothionein gene family in cassava reveals its role in response to physiological stress through the regulation of reactive oxygen species.BMC plant biology · 2023Article
- Changes in physio-biochemical parameters and expression of metallothioneins in Avena sativa L. in response to drought.Scientific reports · 2023Article
- Barley metallothionein isoforms, MT2b2 and MT4, differentially respond to photohormones in barley aleurone layer and their recombinant forms show different affinity for binding to zinc and cadmium.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Article
- Examination of the Metallothionein Gene Family in Greater DuckweedPlants (Basel, Switzerland) · 2022Article
- Isolation and Characterization of thePlants (Basel, Switzerland) · 2022Article
- Metallothionein1A Regulates Rhizobial Infection and Nodulation inInternational journal of molecular sciences · 2022Article
- Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.Biological research · 2022Article
- Over-expression of chickpeaPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Characterization of Brassica rapa metallothionein and phytochelatin synthase genes potentially involved in heavy metal detoxification.PloS one · 2021Article
- Constitutive overexpression of rice metallothionein-like gene OsMT-3a enhances growth and tolerance of Arabidopsis plants to a combination of various abiotic stresses.Journal of plant research · 2020Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
• Expression and regulation of Arabidopsis metallothionein (MT) genes were investigated to examine the functions of MTs in plants. • To examine the tissue-specific expression of MT genes, GUS reporter gene activity driven by promoters of MT1a, MT2a, MT2b and MT3 was analysed in transgenic plants. • MT1a and MT2b are expressed in the phloem of all organs and are copper (Cu)-inducible; MT2a and MT3, by contrast, are expressed predominantly in mesophyll cells and are also induced by Cu in young leaves and at root tips. Expression of MT genes is highly induced by Cu in trichomes and increases during senescence. Expression of MT4 genes is restricted to seeds. • We propose that plant MTs have distinct functions in heavy metal homeostasis, especially for Cu: MT1a and MT2b are involved in the distribution of Cu via the phloem, while MT2a and MT3 chaperone excess metals in mesophyll cells and root tips. These functional capabilities may allow MTs to play a role in mobilization of metal ions from senescing leaves and the sequestration of excess metal ions in trichomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.