Evidence map›Paper›PMID 33872926›Full record

ArticleEnvironment international2021

Residential PM

Joanne E Sordillo, Andres Cardenas, Cancan Qi, Sheryl L Rifas-Shiman, Brent Coull, Heike Luttmann-Gibson, Joel Schwartz, Itai Kloog, Marie-France Hivert, Dawn L DeMeo and 7 more

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Long-Term PMAnnals of the American Thoracic Society · 2025
    Pooled it
  2. Pooled it
  3. Early Life Exposure to Air Pollutants and Childhood Asthma.Current allergy and asthma reports · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Particulate matter-induced epigenetic modifications and lung complications.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  10. Article
  11. Differential DNA methylation in the brain as potential mediator of the association between traffic-related PMAlzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  12. Review
  13. Epigenome-wide association studies of allergic disease and the environment.The Journal of allergy and clinical immunology · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Joanne E SordilloDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Andres CardenasDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, USA.
Cancan QiUniversity of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.
Sheryl L Rifas-ShimanDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Brent CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Heike Luttmann-GibsonDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Itai KloogDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Marie-France HivertDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Dawn L DeMeoChanning Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Andrea A BaccarelliDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, NY, NY, USA.
Cheng-Jian XuResearch Group of Bioinformatics and Computational Genomics, CiiM, Centre for individualized infection medicine, a joint venture between Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany; Department of Gastroenterology, Hepatology and Endocrinology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Ulrike GehringInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
Judith M VonkUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands.
Gerard KoppelmanUniversity of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Diane R GoldDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: redrg@channing.harvard.edu.
Harvard University · USUniversity Medical Center Groningen · NLBrigham and Women's Hospital · USBerkeley Public Health Division · USColumbia University · USRadboud University Nijmegen · NLUtrecht University · NL

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9M
Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2016 to 2020
$12.6M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUH3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2018 to 2022
$11.7M
The Fetal and Childhood Environment, Oxidative Balance, Inflammation and AsthmaR01AI102960 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R, OKEN, EMILY · 2013 to 2017
$4.0M
Early Life DNA Methylation and Childhood Allergic DiseaseR01HL111108 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2013 to 2016
$3.0M
PRENATAL AND POSTNATAL EXPOSURE TO ENVIRONMENTAL MIXTURES: NEURODEVELOPMENT AND DNA METHYLATION BIOMARKERSR01ES031259 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI CARDENAS, ANDRES · 2020 to 2024
$1.9M
NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL111108NIAID NIH HHS R01 AI102960NICHD NIH HHS R01 HD034568NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES031259NIH HHS UH3 OD023286
6 · The paper itself

Abstract

rationalePM

objectivesWe aimed to study associations of fine particulate matter PM

methodsWe conducted nasal epigenome-wide association analyses within 503 children from Project Viva (mean age 12.9 y), and examined various exposure durations (1-day, 1-week, 1-month, 3-months and 1-year) prior to nasal sampling. We used residential addresses to estimate average daily PM

resultsIn adjusted analyses, we found 362 CpGs associated with 1-year PM

conclusionWe observed wide-spread DNAm variability associated with average past year PM

Indexed as

Air PollutionEpigenomeAdolescentChildDNA MethylationHumansNetherlandsParticulate MatterParticulate Matter

Identifiers

PMID33872926
PMCPMC8823376
OpenAlexW3155257494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.