Observational studyAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2021
Recipient Obesity and Kidney Transplant Outcomes: A Mate-Kidney Analysis.
Observational study in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Robot-assisted kidney transplantation in obese recipients: wound-risk reduction, graft safety, and access implications.Journal of robotic surgery · 2026Review
- Clinical Impact of Preoperative Obesity on Living-Donor Kidney Transplant Recipients in Japan: A Multicenter Experience.Journal of clinical medicine · 2026Article
- Cardiovascular-Kidney-Metabolic Disease Burden in Children and Adults Following Heart Transplantation.JACC. Heart failure · 2025Observational
- Should Kidney Transplantation be Offered to Patients with Body Mass Index >40?: CON.Kidney360 · 2025Article
- Impact of Race on Outcomes in Obese Kidney Transplant Recipients: A Mate Kidney Analysis.Journal of racial and ethnic health disparities · 2025Article
- Using Unsupervised Clustering to Characterize Phenotypes Among Older Kidney Transplant Recipients: A Cohort Study.Canadian journal of kidney health and disease · 2025Article
- Body mass index in pediatric kidney transplant selection criteria.Pediatric nephrology (Berlin, Germany) · 2024Article
- Better kidney allograft survival despite higher-risk donor and recipient characteristics between 1995 and 2014.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Future Prospects of Metabolic and Bariatric Surgery: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2024Review
- Assessing Patients beyond the Simple Optics of BMI: The Concomitant Role of Sarcopenia and BMI in Predicting Kidney Transplant Outcomes.Life (Basel, Switzerland) · 2024Article
- Obesity, organ failure, and transplantation: a review of the role of metabolic and bariatric surgery in transplant candidates and recipients.Surgical endoscopy · 2024Review
- Obesity is Associated With Delayed Graft Function in Kidney Transplant Recipients: A Paired Kidney Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Transplant and Recipient Factors in Prediction of Kidney Transplant Outcomes: A UK-Wide Paired Analysis.Journal of clinical medicine · 2022Article
- Risk Due to ABO Incompatibility and Donor-Recipient Weight Mismatch in Living Donor Kidney Transplantation: A National Cohort Study.Journal of clinical medicine · 2021Article
- Kidney Transplantation and Candidate BMI: Viability Is in the Eye of the Beholder.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RATIONALE &
objectiveThe impact of extreme recipient obesity on long-term kidney transplant outcomes has been controversial. This study sought to evaluate the association of various levels of recipient obesity on kidney transplantation outcomes by comparing mate-kidney recipient pairs to address possible confounding effects of donor characteristics on posttransplant outcomes. STUDY
designNationwide observational cohort study using mate-kidney models. SETTING &
participantsIn analysis based on the Organ Procurement and Transplant Network/United Network of Organ Sharing database, 44,560 adult recipients of first-time deceased-donor kidney transplants from 2001 through 2016 were paired by donor. PREDICTORS: Recipient body mass index (BMI) categorized as 18-25 (n = 12,446), >25-30 (n = 15,477), >30-35 (n = 11,144; obese), and >35 (n = 5,493; extreme obesity) kg/m OUTCOMES: Outcomes included patient survival, graft survival, death-censored graft survival, delayed graft function (DGF), and hospital length of stay. ANALYTICAL APPROACH: Conditional logistic regression and stratified proportional hazards models were used to compare outcomes as odds ratios and hazard ratios (HRs), adjusted for recipient and transplant factors, using recipients with a BMI >35 kg/m
resultsAt a median follow-up of 3.9 years, adjusted odds ratios for DGF were 0.42 (95% CI, 0.36-0.48), 0.55 (95% CI, 0.48-0.62), and 0.73 (95% CI, 0.64-0.83) for BMI 18-25, >25-30, and >30-35 kg/m LIMITATIONS: Observational study with limited detail regarding potential confounders.
conclusionsDespite an increased risk of DGF likely unrelated to donor organ quality, long-term transplant outcomes among recipients with a BMI >35 kg/m
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