Evidence map›Paper›PMID 33872146›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2021

Implementation of a Novel 288-Element Dual-Frequency Array for Acoustic Angiography: In Vitro and In Vivo Characterization.

Isabel G Newsome, Thomas M Kierski, Guofeng Pang, Jianhua Yin, Jing Yang, Emmanuel Cherin, F Stuart Foster, Claudia A Carnevale, Christine E M Demore, Paul A Dayton

Abstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Superharmonic and Microultrasound Imaging With Plane Wave Beamforming Techniques.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  2. Article
  3. Article
  4. Acoustic Molecular Imaging Beyond the Diffraction Limit In Vivo.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabel G Newsome
Thomas M Kierski
Guofeng Pang
Jianhua Yin
Jing Yang
Emmanuel Cherin
F Stuart Foster
Claudia A Carnevale
Christine E M Demore
Paul A Dayton

Funding

Pre-doctoral Training Program in Integrative Vascular BiologyT32HL069768 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Christopher P. Mack · 2002 to 2026
$9.7M
Academic-Industrial Partnership for Translation of Acoustic AngiographyR01CA189479 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAYTON, PAUL A · 2014 to 2025
$4.7M
Toward Clinical Translation of Acoustic Angiography: Optimization of Microvascular Ultrasound Imaging on a Novel Dual-frequency ArrayF31CA243177 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NEWSOME, ISABEL · 2019 to 2020
$74k
CIHR FDN148367NCI NIH HHS F31 CA243177NCI NIH HHS R01 CA189479NHLBI NIH HHS T32 HL069768
6 · The paper itself

Abstract

Acoustic angiography is a superharmonic contrast-enhanced ultrasound imaging method that produces high-resolution, 3-D maps of the microvasculature. Previous acoustic angiography studies have used twoelement, annular,mechanicallyactuated transducers(called "wobblers") to image microvasculature in preclinical tumor models with high contrast-to-tissue ratio and resolution, but these earlywobbler transducerscould not achieve the depth and sensitivity required for clinical acoustic angiography. In this work, we present a system for performing acoustic angiography with a novel dual-frequency(DF) transducer-a coaxially stacked DF array (DFA). We evaluate the DFA system bothin vitro andin vivo and demonstrate improvements in sensitivity and imaging depth up to 13.1 dB and 10 mm, respectively, compared with previous wobbler probes.

Indexed as

AngiographyContrast MediaAcousticsTransducersUltrasonographyContrast Media

Identifiers

PMID33872146
PMCPMC8375591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.