Evidence map›Paper›PMID 33872145›Full record

ArticleIEEE transactions on medical imaging2021

Learning-Based Regularization for Cardiac Strain Analysis via Domain Adaptation.

Allen Lu, Shawn S Ahn, Kevinminh Ta, Nripesh Parajuli, John C Stendahl, Zhao Liu, Nabil E Boutagy, Geng-Shi Jeng, Lawrence H Staib, Matthew O'Donnell and 2 more

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Coordinate-Independent 3-D Ultrasound Principal Stretch and Direction Imaging.IEEE transactions on bio-medical engineering · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Spatiotemporal Bayesian Regularization for Cardiac Strain Imaging: Simulation andIEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  8. A Semi-supervised Joint Network for Simultaneous Left Ventricular Motion Tracking and Segmentation in 4D Echocardiography.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Allen Lu
Shawn S Ahn
Kevinminh Ta
Nripesh Parajuli
John C Stendahl
Zhao Liu
Nabil E Boutagy
Geng-Shi Jeng
Lawrence H Staib
Matthew O'Donnell
Albert J Sinusas
James S Duncan

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Medical Scientist Training ProgramT32GM136651 · NIGMS · YALE UNIVERSITY · PI BARBARA I KAZMIERCZAK · 2020 to 2026
$16.5M
q4DE: A Biomarker for Image-Guided, Post-MI Hydrogel TherapyR01HL121226 · NHLBI · YALE UNIVERSITY · PI DUNCAN, JAMES S, O'DONNELL, MATTHEW · 2014 to 2022
$6.3M
Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Image Guided Delivery of Bioresponsive HydrogelsR01HL137365 · NHLBI · YALE UNIVERSITY · PI BURDICK, JASON A, DUNCAN, JAMES S · 2018 to 2021
$3.2M
Deep Learning-based Framework for Segmentation and Motion Tracking of Left Ventricle in 3D EchocardiographyF30HL158154 · NHLBI · YALE UNIVERSITY · PI AHN, SHAWN · 2021 to 2023
$113k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS F30 HL158154NHLBI NIH HHS R01 HL121226NHLBI NIH HHS R01 HL137365NHLBI NIH HHS T32 HL098069NIGMS NIH HHS T32 GM007205NIGMS NIH HHS T32 GM136651
6 · The paper itself

Abstract

Reliable motion estimation and strain analysis using 3D+ time echocardiography (4DE) for localization and characterization of myocardial injury is valuable for early detection and targeted interventions. However, motion estimation is difficult due to the low-SNR that stems from the inherent image properties of 4DE, and intelligent regularization is critical for producing reliable motion estimates. In this work, we incorporated the notion of domain adaptation into a supervised neural network regularization framework. We first propose a semi-supervised Multi-Layered Perceptron (MLP) network with biomechanical constraints for learning a latent representation that is shown to have more physiologically plausible displacements. We extended this framework to include a supervised loss term on synthetic data and showed the effects of biomechanical constraints on the network's ability for domain adaptation. We validated the semi-supervised regularization method on in vivo data with implanted sonomicrometers. Finally, we showed the ability of our semi-supervised learning regularization approach to identify infarct regions using estimated regional strain maps with good agreement to manually traced infarct regions from postmortem excised hearts.

Indexed as

Neural Networks, ComputerSupervised Machine LearningHeartMotion

Identifiers

PMID33872145
PMCPMC8442959

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.