Evidence map›Paper›PMID 33871817›Full record

ReviewDrugs2021

Givosiran: A Review in Acute Hepatic Porphyria.

Yahiya Y Syed

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Designing nucleic acid-based therapeutics for cancer treatment: Updates on the state of the art.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Review
  6. Target, silence, replace: a review on RNA-based drugs in modern medicine.Frontiers in cell and developmental biology · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Delivering living medicines with biomaterials.Nature reviews. Materials · 2025
    Article
  14. Review
  15. Emerging RNAi Therapies to Treat Hypertension.Molecular diagnosis & therapy · 2025
    Review
  16. Nucleic acid drugs: recent progress and future perspectives.Signal transduction and targeted therapy · 2024
    Review
  17. Article
  18. Enhancing RNA-lipid nanoparticle delivery: Organ- and cell-specificity and barcoding strategies.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  19. Review
  20. Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yahiya Y SyedSpringer Nature, Mairangi Bay, Private Bag 65901, Auckland, 0754, New Zealand. demail@springer.com.
Springer Nature (New Zealand) · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Givosiran (Givlaari

Indexed as

5-Aminolevulinate SynthetaseAcetylgalactosamineAcute Kidney InjuryChemical and Drug Induced Liver InjuryDrug InteractionsHeminHospitalizationHumansPainPorphobilinogen SynthasePorphyria, Acute IntermittentPorphyrias, HepaticPyrrolidinesRandomized Controlled Trials as TopicRNA, Small InterferingSeverity of Illness Index5-Aminolevulinate SynthetaseAcetylgalactosamineALAS1 protein, humangivosiranHeminPorphobilinogen SynthasePyrrolidinesRNA, Small Interfering

Identifiers

PMID33871817
OpenAlexW3154543553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.