Evidence map›Paper›PMID 33871737›Full record

ArticleBrain topography2021

Resting-State EEG Microstates Parallel Age-Related Differences in Allocentric Spatial Working Memory Performance.

Adeline Jabès, Giuliana Klencklen, Paolo Ruggeri, Christoph M Michel, Pamela Banta Lavenex, Pierre Lavenex

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain topography, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  3. [Microstate dynamics in motor imagery of stroke patients with transcranial alternating current stimulation modulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Adeline JabèsLaboratory of Brain and Cognitive Development, Institute of Psychology, University of Lausanne, 1015, Lausanne, Switzerland.
Giuliana KlencklenLaboratory of Brain and Cognitive Development, Institute of Psychology, University of Lausanne, 1015, Lausanne, Switzerland.
Paolo RuggeriLaboratory of Brain and Cognitive Development, Institute of Psychology, University of Lausanne, 1015, Lausanne, Switzerland.
Christoph M MichelFunctional Brain Mapping Laboratory, University of Geneva, 1202, Geneva, Switzerland.
Pamela Banta LavenexLaboratory of Brain and Cognitive Development, Institute of Psychology, University of Lausanne, 1015, Lausanne, Switzerland.
Pierre LavenexLaboratory of Brain and Cognitive Development, Institute of Psychology, University of Lausanne, 1015, Lausanne, Switzerland. pierre.lavenex@unil.ch.ORCID 0000-0002-9278-1312
University of Lausanne · CHUniDistance Suisse · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations of resting-state EEG microstates have been associated with various neurological disorders and behavioral states. Interestingly, age-related differences in EEG microstate organization have also been reported, and it has been suggested that resting-state EEG activity may predict cognitive capacities in healthy individuals across the lifespan. In this exploratory study, we performed a microstate analysis of resting-state brain activity and tested allocentric spatial working memory performance in healthy adult individuals: twenty 25-30-year-olds and twenty-five 64-75-year-olds. We found a lower spatial working memory performance in older adults, as well as age-related differences in the five EEG microstate maps A, B, C, C' and D, but especially in microstate maps C and C'. These two maps have been linked to neuronal activity in the frontal and parietal brain regions which are associated with working memory and attention, cognitive functions that have been shown to be sensitive to aging. Older adults exhibited lower global explained variance and occurrence of maps C and C'. Moreover, although there was a higher probability to transition from any map towards maps C, C' and D in young and older adults, this probability was lower in older adults. Finally, although age-related differences in resting-state EEG microstates paralleled differences in allocentric spatial working memory performance, we found no evidence that any individual or combination of resting-state EEG microstate parameter(s) could reliably predict individual spatial working memory performance. Whether the temporal dynamics of EEG microstates may be used to assess healthy cognitive aging from resting-state brain activity requires further investigation.

Indexed as

ElectroencephalographyMemory, Short-TermAgedBrainBrain MappingCognitionHumansElectroencephalographyHealthy agingMicrostatesSpontaneous brain activityWorking memory performance

Identifiers

PMID33871737
PMCPMC8195770
OpenAlexW3152821811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.