Evidence map›Paper›PMID 33871707›Full record

ArticleEuropean radiology2021

Real-time US/cone-beam CT fusion imaging for percutaneous ablation of small renal tumours: a technical note.

Lorenzo Monfardini, Nicolò Gennaro, Franco Orsi, Paolo Della Vigna, Guido Bonomo, Gianluca Varano, Luigi Solbiati, Giovanni Mauri

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In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Robotic CBCT meets robotic ultrasound.International journal of computer assisted radiology and surgery · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lorenzo MonfardiniDivision of Interventional Radiology, Fondazione Poliambulanza, 25124, Brescia, Italy. lorenzo.monfardini@poliambulanza.it.ORCID http://orcid.org/0000-0002-7544-4170
Nicolò GennaroDepartament of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Italy.
Franco OrsiDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Paolo Della VignaDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Guido BonomoDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Gianluca VaranoDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Luigi SolbiatiDepartament of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Italy.
Giovanni MauriDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITHumanitas University · ITFondazione Poliambulanza Istituto Ospedaliero · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFusion imaging is gaining attention as an imaging technique to assist minimally invasive tumour ablation. Ultrasound (US) and computed tomography (CT) are the most common imaging modalities to guide thermal ablation of renal tumours, yet cone-beam CT (CBCT) has recently been described to successfully assist percutaneous renal interventions. Our goal was to evaluate primary technical success and correct lesion targeting of US/CBCT fusion imaging to guide the ablation of kidney masses < 2 cm in a small group of patients. MATERIAL AND

methodsSix renal lesions (maximum diameter 11-17 mm) were treated with RFA in 5 different patients using real-time US/CBCT. Fusion imaging was used to identify and monitor tumour ablation. Demographics, tumour characteristics and mean serum creatinine levels were recorded before and after the procedure. Primary technical success and correct lesion targeting represented the main endpoints of the study. Primary technique efficacy was confirmed at 1-month and 3-month contrast-enhanced CT follow-ups.

resultsIn all cases, a confident US/CBCT synchronisation was reached and allowed for a correct targeting and a successful percutaneous ablation. Primary technique efficacy was 100%. No recurrence was observed at the follow-up that ranged from 8 to 26 months (mean 16 months).

conclusionsUS/CBCT fusion proved to be a viable method to precisely guide safe and effective percutaneous thermal ablation in patients with small renal tumours, especially when hardly detectable on US. KEY POINTS: • US/CBCT fusion imaging for renal ablation is safe and feasible. • US/CBCT fusion imaging allows for an improved targeting and complete ablation of small RCC with poor US-conspicuity.

Indexed as

Catheter AblationKidney NeoplasmsCone-Beam Computed TomographyHumansKidneyNeoplasm Recurrence, LocalRetrospective StudiesTreatment OutcomeCone-beam CT (CBCT)KidneyRadiologyRenal cell carcinoma (RCC)Therapeutics

Identifiers

PMID33871707
OpenAlexW3153064455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.