ArticleJAMA network open2021
Association of Postoperative Infections After Fractures With Long-term Income Among Adults.
Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- The Role of Negative-Pressure Wound Therapy in Patients with Fracture-Related Infection: A Systematic Review and Critical Appraisal.BioMed research international · 2021Pooled it
- Clinical Outcome After Surgery for Fracture-Related Infection Is Dependent on Both Microbiology and the Host Inflammatory Response.Pathogens (Basel, Switzerland) · 2026Article
- Review
- Orthopedic Trauma Management: A Comprehensive Review of Surgical Interventions, Rehabilitation, and Patient Outcomes.Cureus · 2026Review
- Investigating long-term quality of life and depressive symptoms following fracture-related infection: a systematic review with meta-analysis of heterogeneous evidence.Journal of bone and joint infection · 2026Review
- Disparities Exist in the Experience of Financial Burden Among Orthopedic Trauma Patients: A Systematic Review.Current reviews in musculoskeletal medicine · 2024Review
- The surgical management of fracture-related infection. Surgical strategy selection and the need for early surgical intervention.Journal of orthopaedics · 2024Article
- Incidence and impact of surgical site complications on length of stay and cost of care for patients undergoing open procedures.Surgery open science · 2023Article
- Quotation errors related to the wound management of open lower limb fractures (WOLLF) randomized clinical trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Review
- Multidisciplinary Treatment of Fracture-Related Infection Has a Positive Impact on Clinical Outcome-A Retrospective Case Control Study at a Tertiary Referral Center.Antibiotics (Basel, Switzerland) · 2023Article
- The patients' perspective - a qualitative analysis of experiencing a fracture-related infection.Frontiers in psychology · 2023Article
- The intersection of fracture healing and infection: Orthopaedics research society workshop 2021.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Review
- Direct Healthcare Cost of Fracture-related Infection Treatment.JB & JS open accessArticle
- Deep Surgical Site Infection after Fracture Has a Profound Effect on Functional Outcomes.JB & JS open accessArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Importance: Postoperative infections after a fracture exert tremendous costs on the health care system. However, the patient economic burden associated with a postoperative infection is unclear. Objective: To evaluate the association between a postoperative infection and long-term income among patients with surgically treated fractures. Design, Setting, and Participants: A retrospective cohort study linked academic trauma center data with Maryland tax records using inverse probability of treatment weighting to estimate between-group differences among 11 673 adults who underwent surgery to treat fractures of the extremities or pelvis between January 1, 2003, and December 31, 2016. Statistical analysis was performed from November 5, 2019, to August 30, 2020. Exposure: A postoperative infection within 1 year of injury. Main Outcomes and Measures: The primary outcome was the annual household income up to 6 years after injury. Household income incorporates multiple types of income, including wage earnings, taxable Social Security benefits, workers' compensation, and disability benefits. Secondary outcomes included individual earnings, Social Security benefits, unemployment benefits, and catastrophic income loss. Results: The study included 11 673 patients (7756 male patients [66.4%]; mean [SD] age, 45.2 [19.2] years) with a mean (SD) preinjury household income of $30 505 ($89 030). A total of 403 patients (3.5%) had a postoperative infection. Postoperative infections were associated with a $6080 annual decrease (95% CI, -$12 114 to -$47; P = .048) in household income in the 6 years after injury. Postoperative infections were associated with a 6.6% increase (95% CI, 4.9%-8.3%; P < .001) in the risk of catastrophic wage loss within 2 years of the fracture and were associated with a 45% increase in the odds of receiving Social Security benefits (odds ratio, 1.45; 95% CI, 1.25-1.68; P < .001). However, incurring a postoperative infection was not associated with an increase in the value of the Social Security benefits received. Conclusions and Relevance: This study suggests that postoperative infections have significant and sustained income-associated implications for patients who experience a fracture. Current Social Security mechanisms may not offset the decreased income.
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