Evidence map›Paper›PMID 33871615›Full record

ArticleJAMA network open2021

Association of Postoperative Infections After Fractures With Long-term Income Among Adults.

Nathan N O'Hara, C Daniel Mullins, Gerard P Slobogean, Anthony D Harris, Dionne S Kringos, Niek S Klazinga

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Quotation errors related to the wound management of open lower limb fractures (WOLLF) randomized clinical trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Review
  10. Article
  11. Article
  12. The intersection of fracture healing and infection: Orthopaedics research society workshop 2021.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nathan N O'HaraDepartment of Orthopaedics, University of Maryland School of Medicine, Baltimore.
C Daniel MullinsDepartment of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore.
Gerard P SlobogeanDepartment of Orthopaedics, University of Maryland School of Medicine, Baltimore.
Anthony D HarrisDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.
Dionne S KringosDepartment of Public and Occupational Health, Amsterdam Universitair Medische Centra, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Niek S KlazingaDepartment of Public and Occupational Health, Amsterdam Universitair Medische Centra, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
University of Maryland, Baltimore · USAmsterdam University Medical Centers · NLUniversity of Amsterdam · NL

Funding

A Planning Grant for a Multi-Center Randomized Controlled Trial Comparing Resection and Endoprosthetic Reconstruction vs. Internal Fixation for Metastatic Bone Disease of the Proximal FemurR34AR084146 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI GHERT, MICHELLE, O'HARA, NATHAN NOEL · 2024 to 2025
$297k
AHRQ HHS R03 HS027218NIAMS NIH HHS R34 AR084146
6 · The paper itself

Abstract

Importance: Postoperative infections after a fracture exert tremendous costs on the health care system. However, the patient economic burden associated with a postoperative infection is unclear. Objective: To evaluate the association between a postoperative infection and long-term income among patients with surgically treated fractures. Design, Setting, and Participants: A retrospective cohort study linked academic trauma center data with Maryland tax records using inverse probability of treatment weighting to estimate between-group differences among 11 673 adults who underwent surgery to treat fractures of the extremities or pelvis between January 1, 2003, and December 31, 2016. Statistical analysis was performed from November 5, 2019, to August 30, 2020. Exposure: A postoperative infection within 1 year of injury. Main Outcomes and Measures: The primary outcome was the annual household income up to 6 years after injury. Household income incorporates multiple types of income, including wage earnings, taxable Social Security benefits, workers' compensation, and disability benefits. Secondary outcomes included individual earnings, Social Security benefits, unemployment benefits, and catastrophic income loss. Results: The study included 11 673 patients (7756 male patients [66.4%]; mean [SD] age, 45.2 [19.2] years) with a mean (SD) preinjury household income of $30 505 ($89 030). A total of 403 patients (3.5%) had a postoperative infection. Postoperative infections were associated with a $6080 annual decrease (95% CI, -$12 114 to -$47; P = .048) in household income in the 6 years after injury. Postoperative infections were associated with a 6.6% increase (95% CI, 4.9%-8.3%; P < .001) in the risk of catastrophic wage loss within 2 years of the fracture and were associated with a 45% increase in the odds of receiving Social Security benefits (odds ratio, 1.45; 95% CI, 1.25-1.68; P < .001). However, incurring a postoperative infection was not associated with an increase in the value of the Social Security benefits received. Conclusions and Relevance: This study suggests that postoperative infections have significant and sustained income-associated implications for patients who experience a fracture. Current Social Security mechanisms may not offset the decreased income.

Indexed as

Fracture FixationAdultAgedFemaleFractures, BoneHumansIncomeMaleMiddle AgedSalaries and Fringe BenefitsSocial SecuritySurgical Wound Infection

Identifiers

PMID33871615
PMCPMC8056283
OpenAlexW3156477270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.