Evidence map›Paper›PMID 33871387›Full record

ArticleJournal of the Chinese Medical Association : JCMA2021

Adherence to healthy lifestyle improved clinical outcomes in coronary artery disease patients after coronary intervention.

Ya-Ling Yang, Hsin-Bang Leu, Wei-Hsian Yin, Wei-Kung Tseng, Yen-Wen Wu, Tsung-Hsien Lin, Hung-I Yeh, Kuan-Cheng Chang, Ji-Hung Wang, Chau-Chung Wu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. To do one and to get more: Part I. Diabetes and bone.Journal of the Chinese Medical Association : JCMA · 2022
    Review
  7. Dipeptidyl peptidase-4 inhibitors and osteoporosis.Journal of the Chinese Medical Association : JCMA · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Ya-Ling YangDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital Taoyuan Branch, Taoyuan, Taiwan, ROC.
Hsin-Bang LeuCardiovascular Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
Wei-Hsian YinDivision of Cardiology, Heart Center, Cheng-Hsin General Hospital, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Wei-Kung TsengDepartment of Medical Imaging and Radiological Sciences, I-Shou University, Kaohsiung, Taiwan, ROC.
Yen-Wen WuCardiology Division of Cardiovascular Medical Center and Department of Nuclear Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan, ROC.
Tsung-Hsien LinDivision of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Hung-I YehMackay Memorial Hospital, Mackay Medical College, New Taipei City, Taiwan, ROC.
Kuan-Cheng ChangDivision of Cardiology, Department of Internal Medicine, China Medical University Hospital, Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, ROC.
Ji-Hung WangDepartment of Cardiology, Buddhist Tzu-Chi General Hospital, Tzu-Chi University, Hualien, Taiwan, ROC.
Chau-Chung WuDivision of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan, ROC.
Jaw-Wen ChenCardiovascular Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
Taipei Veterans General Hospital · TWCheng Hsin General Hospital · TWChina Medical University Hospital · TWE-Da Hospital · TWFar Eastern Memorial Hospital · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWMackay Medical College · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLifestyle modification is suggested for patients with coronary artery disease (CAD), but the impact of adherence to a healthy lifestyle remains undetermined. The aim of this study is to investigate the association of adherence to a healthy lifestyle with future outcomes and biochemical markers in CAD patients.

methodsThe Biosignature CAD study examined 716 CAD patients who underwent a percutaneous coronary intervention (PCI). Information was collected on whether these patients adhered to a healthier lifestyle after PCI, including healthy diet, not smoking, and exercise. The clinical outcomes included major cardiovascular events and unplanned revascularization procedures, hospitalization for refractory or unstable angina, and other causes.

resultsThe average follow-up period was 26.8 ± 8.1 months, during which 175 (24.4%) patients experienced at least one event. The combination of healthy lifestyle factors was associated with lower risk, and the maximum risk reduction reached 50% (hazard ratio: 0.50, 95% confidence interval: 0.25-0.99). As the number of healthy lifestyle factors increased, there were decreases in inflammatory markers, C-reactive protein, waist circumference, low-density lipoprotein cholesterol, and the ratio of total cholesterol to high-density lipoprotein (HDL) cholesterol (p < 0.05). The benefits of modifiable healthy lifestyle factors were especially observed in the younger population, males, patients with HDL <40 mg/dL, those with reduced left ventricular ejection fraction, and those receiving statin therapy.

conclusionAdherence to a healthy lifestyle is independently associated with a lower risk of future adverse events in CAD patients and plays an important role in secondary prevention in the era of interventional cardiology.

Indexed as

Coronary Artery DiseaseLife StyleOutcome Assessment, Health CarePatient ComplianceAgedFemaleHumansMaleMiddle AgedTaiwan

Identifiers

PMID33871387
PMCPMC12966064
OpenAlexW3156724719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.