ArticleeLife2021
Spontaneous and evoked activity patterns diverge over development.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Nitric oxide refines retinal circuit architecture independently of retinal wave dynamics.Cell death discovery · 2026Article
- Zebrafish Ace2N-mNeon expression toolkit forNeurophotonics · 2026Article
- [Research on the relationship between resting-state spontaneous electroencephalography and task-evoked electroencephalography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Review
- The developmental emergence of reliable cortical representations.Nature neuroscience · 2025Article
- Flexibility of intrinsic neural timescales during distinct behavioral states.Communications biology · 2024Article
- Orthogonalization of spontaneous and stimulus-driven activity by hierarchical neocortical areal network in primates.Nature communications · 2024Article
- Fantastic beasts and how to study them: rethinking experimental animal behavior.The Journal of experimental biology · 2024Article
- Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number.bioRxiv : the preprint server for biology · 2024Article
- Revealing and reshaping attractor dynamics in large networks of cortical neurons.PLoS computational biology · 2024Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.Current biology : CB · 2023Article
- Repeated passive visual experience modulates spontaneous and non-familiar stimuli-evoked neural activity.Scientific reports · 2023Article
- A role for cortical interneurons as adversarial discriminators.PLoS computational biology · 2023Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.bioRxiv : the preprint server for biology · 2023Article
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- Brain mechanisms of mental processing: from evoked and spontaneous brain activities to enactive brain activity.Psychoradiology · 2023Review
- Step by step: cells with multiple functions in cortical circuit assembly.Nature reviews. Neuroscience · 2022Review
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Authors and funding
6 authors.
Funding
Abstract
The immature brain is highly spontaneously active. Over development this activity must be integrated with emerging patterns of stimulus-evoked activity, but little is known about how this occurs. Here we investigated this question by recording spontaneous and evoked neural activity in the larval zebrafish tectum from 4 to 15 days post-fertilisation. Correlations within spontaneous and evoked activity epochs were comparable over development, and their neural assemblies refined in similar ways. However, both the similarity between evoked and spontaneous assemblies, and also the geometric distance between spontaneous and evoked patterns, decreased over development. At all stages of development, evoked activity was of higher dimension than spontaneous activity. Thus, spontaneous and evoked activity do not converge over development in this system, and these results do not support the hypothesis that spontaneous activity evolves to form a Bayesian prior for evoked activity.
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