ArticleAngewandte Chemie (International ed. in English)2021
Three-Component Aminoarylation of Electron-Rich Alkenes by Merging Photoredox with Nickel Catalysis.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Photocatalytic multicomponent alkene dicarbofunctionalizationChemical science · 2026Article
- Photocatalytic Aminoarylation of Styrenes.Organic letters · 2026Article
- Photocatalytic streamlined dual-functional group transfer from cyanopyridine to internal alkynes.Nature communications · 2025Article
- Nickel-photoredox catalysis: merging photons with metal catalysts for organic synthesis.RSC advances · 2025Review
- Merging Hydrogen-Atom-Transfer and the Truce-Smiles Rearrangement for Synthesis of β-Arylethylamines from Unactivated Allylsulfonamides.Angewandte Chemie (International ed. in English) · 2025Article
- Transition Metal Catalysis for the Asymmetric Synthesis of 2-Arylethylamines: A Review of the New Millennium.Molecules (Basel, Switzerland) · 2025Review
- A General Amino-(Hetero)arylation of Simple Olefins with (Hetero)aryl Sulfonamides Enabled by anACS catalysis · 2025Article
- Aminoalkylation of Alkenes Enabled by Triple Radical Sorting.Journal of the American Chemical Society · 2025Article
- Phosphinothio(seleno)ation of alkynes/olefins and application on the late-stage functionalization of natural products.Communications chemistry · 2024Article
- Article
- Stereoselective Fe-Catalyzed Decoupled Cross-Couplings: Chiral Vinyl Oxazolidinones as Effective Radical Lynchpins for Diastereoselective C(spACS catalysis · 2024Article
- Chiral arylsulfinylamides as reagents for visible light-mediated asymmetric alkene aminoarylations.Nature chemistry · 2024Article
- Photoinduced Copper-Catalyzed Late-Stage Azidoarylation of Alkenes via Arylthianthrenium Salts.Journal of the American Chemical Society · 2023Article
- Dual Nickel/Photoredox-Catalyzed Asymmetric Carbosulfonylation of Alkenes.Journal of the American Chemical Society · 2023Article
- Metal-free photosensitized radical relay 1,4-carboimination across two distinct olefins.Chemical science · 2023Article
- Recent progress in the chemistry of β-aminoketones.RSC advances · 2022Review
- Formal β-C-H Arylation of Aldehydes and Ketones by Cooperative Nickel and Photoredox Catalysis.Angewandte Chemie (International ed. in English) · 2022Article
- Three-component carboacylation of alkenesChemical science · 2022Article
- Catalytic intramolecular aminoarylation of unactivated alkenes with aryl sulfonamides.Chemical science · 2022Article
- Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.Chemistry, an Asian journal · 2022Review
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4 authors.
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Abstract
A three-component 1,2-aminoarylation of vinyl ethers, enamides, ene-carbamates and vinyl thioethers by synergistic photoredox and nickel catalysis is reported. 2,2,2-Trifluoroethoxy carbonyl protected α-amino-oxy acids are used as amidyl radical precursors. anti-Markovnikov addition of the amidyl radical to the alkene and Ni-mediated radical/transition metal cross over lead to the corresponding 1,2-aminoarylation product. The radical cascade, which can be conducted under practical and mild conditions, features high functional group tolerance and broad substrate scope. Stereoselective 1,2-aminoarylation is achieved using a L-(+)-lactic acid derived vinyl ether as the substrate, offering a novel route for the preparation of protected enantiopure α-arylated β-amino alcohols. In addition, 1,2-aminoacylation of vinyl ethers is achieved by using an acyl succinimide as the electrophile for the Ni-mediated radical coupling.
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