Evidence map›Paper›PMID 33870862›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2021

Influence of vitamin D treatment on functional expression of drug disposition pathways in human kidney proximal tubule cells during simulated uremia.

Stacey M Tuey, Amandla Atilano-Roque, Georgia Charkoftaki, Joshua M Thurman, Thomas D Nolin, Melanie S Joy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Stacey M TueyDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-0946-3506
Amandla Atilano-RoqueDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Georgia CharkoftakiDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Joshua M ThurmanDivision of Nephrology and Hypertension, School of Medicine, University of Colorado, Aurora, CO, USA.
Thomas D NolinDepartment of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.
Melanie S JoyDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
University of Colorado Anschutz Medical Campus · USUniversity of Pittsburgh · USYale University · US

Funding

Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney DiseaseR01GM107122 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI JOY, MELANIE S, NOLIN, THOMAS DOUGLAS · 2014 to 2018
$2.3M
NIGMS NIH HHS R01 GM107122
6 · The paper itself

Abstract

Effects of cholecalciferol (VitD

Indexed as

Organic Anion TransportersPharmaceutical PreparationsUremiaCholecalciferolHumansKidneyVitamin DCholecalciferolOrganic Anion TransportersPharmaceutical PreparationsSLCO4C1 protein, humanVitamin Dcell cultureCYP enzymesorganic anion transporterP-glycoproteinproximal tubule cellsRenal metabolismrenal transporturaemiavitamin D

Identifiers

PMID33870862
PMCPMC12088830
OpenAlexW3156247426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.