Evidence map›Paper›PMID 33870785›Full record

Trial reportMultiple sclerosis (Houndmills, Basingstoke, England)2021

Home-based Pilates for symptoms of anxiety, depression and fatigue among persons with multiple sclerosis: An 8-week randomized controlled trial.

Karl M Fleming, Susan B Coote, Matthew P Herring

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Multiple sclerosis (Houndmills, Basingstoke, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04120207 (An Eight-week Randomised Controlled Trial of Home-based Pilates for Symptoms of Anxiety, Depression, and Fatigue Among People With MS With Minimal-to-mild Mobility Disability), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04120207 nacompletednot on this map

An Eight-week Randomised Controlled Trial of Home-based Pilates for Symptoms of Anxiety, Depression, and Fatigue Among People With MS With Minimal-to-mild Mobility Disability: Study Protocol

TypeinterventionalSponsorUniversity of LimerickRan2019 to 2019Enrolled63ConditionsMultiple SclerosisArmsHome-based Pilates, Delayed-start Pilates
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karl M FlemingPhysical Activity for Health Research Cluster, Health Research Institute, University of Limerick, Limerick, Ireland/Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.ORCID 0000-0002-3770-5931
Susan B CootePhysical Activity for Health Research Cluster, Health Research Institute, University of Limerick, Limerick, Ireland/School of Allied Health, University of Limerick, and Multiple Sclerosis Society, Limerick, Ireland.
Matthew P HerringPhysical Activity for Health Research Cluster, Health Research Institute, University of Limerick, Limerick, Ireland/Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.ORCID 0000-0002-6835-5321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSymptoms of anxiety, depression and fatigue are common comorbidities among persons with multiple sclerosis (PwMS). A previous pilot study supported Pilates as a feasible exercise modality that may improve these outcomes among PwMS.

objectiveTo quantify the effects of 8 weeks of home-based Pilates on symptoms of anxiety, depression and fatigue among PwMS.

methodsA total of 80 PwMS (69 female) were randomized to twice-weekly home-based Pilates guided by a DVD) or wait-list control. Validated questionnaires assessed anxiety, depressive and fatigue symptoms at baseline, weeks 2, 4, 6 and 8. Using intention to treat, repeated measures analysis of covariance (RM-ANCOVA) adjusted for baseline physical activity examined between-group differences across time. Hedges'

resultsGroup × time interactions were statistically significant for all outcomes (all

conclusionHome-based Pilates significantly improved anxiety, depressive and fatigue symptoms among PwMS with minimal-to-mild mobility disability, including moderate-to-large, clinically meaningful improvements in depressive and fatigue symptoms.Trial Registration: ClinicalTrials.gov (NCT04120207).

Indexed as

Multiple SclerosisAnxietyDepressionFatigueFemaleHumansPilot Projectsanxietydepressionfatiguemultiple sclerosisPilates

Identifiers

PMID33870785
PMCPMC8597189

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.