Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors at 2 institutions in 1 country.
Tammy YingThe Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Thea GoldenDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0002-7643-8944
Lan ChengInstitute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jeff IshibashiInstitute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Patrick SealeInstitute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Rebecca A SimmonsDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0002-2901-8904
University of Pennsylvania · USChildren's Hospital of Philadelphia · US
Funding
VIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL A. LAZAR · 1986 to 2026
$48.3M
Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Translational Research Training Program in Environmental Health SciencesT32ES019851 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Kara A Bernstein, Trevor M Penning · 2012 to 2026
$6.0M
Regulation of Mesenchymal Progenitor Cell Fate and Adipose Tissue RemodelingR01DK120982 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Patrick Seale · 2019 to 2026
$3.7M
MECHANISMS BY WHICH IUGR LEADS TO DIABETESR01DK055704 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SIMMONS, REBECCA A · 2000 to 2014
$3.6M
Mechanisms by Which IUGR Leads to DiabetesR01DK114054 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SIMMONS, REBECCA A · 2017 to 2020
$1.9M
Metabolic Control of Adipose Tissue Remodeling and FibrosisR01DK123356 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SEALE, PATRICK · 2019 to 2022
$1.9M
HHS | National Institutes of Health (NIH) DK114054HHS | National Institutes of Health (NIH) P30DK19525NIDDK NIH HHS P30 DK019525NIDDK NIH HHS R01 DK055704NIDDK NIH HHS R01 DK114054NIDDK NIH HHS R01 DK120982NIDDK NIH HHS R01 DK123356NIEHS NIH HHS P30 ES013508NIEHS NIH HHS T32 ES019851
6 · The paper itself
Abstract
The cytokine interleukin 4 (IL-4) can increase beige adipogenesis in adult rodents. However, neonatal animals use a distinct adipocyte precursor compartment for adipogenesis as compared with adults. In this study, we address whether IL-4 can induce persistent effects on adipose tissue when administered subcutaneously in the interscapular region during the neonatal period in Sprague-Dawley rats. We injected IL-4 into neonatal male rats during
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Neonatal IL-4 exposure decreases adipogenesis of male rats into adulthood. · full record | OpenQuestion