Evidence map›Paper›PMID 33870475›Full record

ArticleJournal of assisted reproduction and genetics2021

Three ways of knowing: the integration of clinical expertise, evidence-based medicine, and artificial intelligence in assisted reproductive technologies.

Gerard Letterie

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. AI in Childbirth and Emerging Alternatives to Traditional Fertility Treatments.Reproductive sciences (Thousand Oaks, Calif.) · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. GYNs at the REI gates: unsolvable conundrum or unambiguous opportunity?Journal of assisted reproduction and genetics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Proceedings of the first world conference on AI in fertility.Journal of assisted reproduction and genetics · 2023
    Article
  14. Reconsidering evidence-based management of endometriosis.Facts, views & vision in ObGyn · 2022
    Article
  15. Artificial intelligence-the future is now.Journal of assisted reproduction and genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gerard LetterieSeattle Reproductive Medicine, 1505 Westlake Avenue, Suite 400, Seattle, WA, 98104, USA. Gerard.letterie@seattlefetility.com.ORCID http://orcid.org/0000-0001-9447-3295
Seattle Reproductive Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decision-making in fertility care is on the cusp of a significant frameshift. Online tools to integrate artificial intelligence into the decision-making process across all aspects of ART are rapidly emerging. These tools have the potential to improve outcomes and transition decision-making from one based on traditional provider centric assessments toward a hybrid triad of expertise, evidence, and algorithmic data analytics using AI. We can look forward to a time when AI will be the third part of a provider's tool box to complement expertise and medical literature to enable ever more accurate predictions and outcomes in ART. In their fully integrated format, these tools will be part of a digital fertility ecosystem of analytics embedded within an EMR. To date, the impact of AI on ART outcomes is inconclusive. No prospective studies have shown clear cut benefit or cost reductions over current practices, but we are very early in the process of developing and evaluating these tools. We owe it to ourselves to begin to examine these AI-driven analytics and develop a very clear idea about where we can and should go before we roll these tools into clinical care. Thoughtful scrutiny is essential lest we find ourselves in a position of trying to modulate and modify after entry of these tools into our clinics and patient care. The purpose of this commentary is to highlight the evolution and impact AI has had in other fields relevant to the fertility sector and describe a vision for applications within ART that could improve outcomes, reduce costs, and positively impact clinical care.

Indexed as

Artificial IntelligenceDecision Support Systems, ClinicalEvidence-Based MedicineImage Processing, Computer-AssistedReproductive Techniques, AssistedElectronic Health RecordsFemaleFertilization in VitroHumansOocytesPrecision MedicineArtificial intelligenceConvolutional neural networksDecision support systemsDeep learningElectronic medical recordsFeature engineeringImage analysisPersonalized medicine

Identifiers

PMID33870475
PMCPMC8324699
OpenAlexW3154000186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.