ArticleEClinicalMedicine2021
Impact of follow up blood cultures on outcomes of patients with community-onset gram-negative bloodstream infection.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Female Sex and Mortality in Patients With Gram-Negative Bacteremia: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Association of Follow-up Blood Cultures With Mortality in Patients With Gram-Negative Bloodstream Infections: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Article
- Fulminant Aeromonas caviae bacteremia with migratory myalgia: a case report of a CTX-M-3-producing multidrug-resistant strain.BMC infectious diseases · 2026Article
- The impact of follow-up blood cultures on mortality and management in patients with gram-negative bloodstream infections: a validation cohort study.BMC infectious diseases · 2026Article
- Clinical and Genomic Characterization of Serratia Bloodstream Infections.CMI communications · 2025Article
- Age-Related Comparative Study of In-Hospital Mortality, Functional Outcome, and Recurrence in a Large Cohort of Patients Surgically Treated for Chronic Subdural Hematoma.Journal of clinical medicine · 2025Article
- Early follow-up blood cultures-frequency and outcomes of repeat blood culture collection within 48 hours of emergency department workup: an observational study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Article
- Article
- Epidemiology and clinical relevance of persistent bacteraemia in patients with Gram-negative bloodstream infection: a retrospective cohort study.The Journal of antimicrobial chemotherapy · 2024Article
- Risk factors for positive follow-up blood cultures in Gram-negative bacteremia among immunocompromised patients with neutropenia.Transplant infectious disease : an official journal of the Transplantation Society · 2024Article
- The effect of follow-up blood cultures on mortality and antibiotic use in gram-negative bloodstream infections.BMC infectious diseases · 2023Article
- Clinical and Molecular Analyses of Recurrent Gram-Negative Bloodstream Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Association of Repeated Blood Cultures With Mortality in Adult Patients With Gram-Negative Bacilli Bacteremia: A Systematic Review and Meta-analysis.Open forum infectious diseases · 2022Article
- Impact of a Multistep Bundles Intervention in the Management and Outcome of Gram-Negative Bloodstream Infections: A Single-Center "Proof-of-Concept" Study.Open forum infectious diseases · 2022Article
- Follow-up Blood Culture Practices for Gram-Negative Bloodstream Infections in Immunocompromised Hosts at a Large Academic Medical Center.Open forum infectious diseases · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of follow up blood cultures (FUBC) in the management of gram-negative bloodstream infection (GN-BSI) remains controversial. This retrospective cohort study examines the association between obtaining FUBC and mortality in GN-BSI.
methodsHospitalized adults with community-onset GN-BSI at Prisma Health-Midlands hospitals in South Carolina, USA from January 1, 2010 to June 30, 2015 were identified. Patients who died or were discharged from hospital within 72 h were excluded to minimize impact of survival and selection biases on results, respectively. Multivariate Cox proportional hazards regression was used to examine association between obtaining FUBC and 28-day all-cause mortality after adjustment for the propensity to obtain FUBC.
findingsAmong 766 patients with GN-BSI, 219 (28.6%) had FUBC obtained and 15 of 219 (6.8%) FUBC were persistently positive. Overall, median age was 67 years, 438 (57%) were women, 457 (60%) had urinary source of infection, and 426 (56%) had BSI due to
interpretationImproved survival in hospitalized patients with GN-BSI who had FUBC is consistent with the results of recent publications from Italy and North Carolina supporting utilization of FUBC in management of GN-BSI.
fundingThis study had no funding source.
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