Evidence map›Paper›PMID 33869993›Full record

ArticleJBMR plus2021

Bone Geometry Is Altered by Follistatin-Induced Muscle Growth in Young Adult Male Mice.

Audrey S M Chan, Narelle E McGregor, Ingrid J Poulton, Justin P Hardee, Ellie H-J Cho, T John Martin, Paul Gregorevic, Natalie A Sims, Gordon S Lynch

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Search for Ancient Selection Traces in Faverolle Chicken Breed (Animals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Article
  6. Exerkines and myokines in aging sarcopenia.Frontiers in endocrinology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Audrey S M ChanCentre for Muscle Research, Department of Anatomy and Physiology, School of Biomedical Sciences University of Melbourne Melbourne 3010 Australia.ORCID https://orcid.org/0000-0002-9417-0718
Narelle E McGregorSt. Vincent's Institute of Medical Research Fitzroy 3065 Australia.
Ingrid J PoultonSt. Vincent's Institute of Medical Research Fitzroy 3065 Australia.
Justin P HardeeCentre for Muscle Research, Department of Anatomy and Physiology, School of Biomedical Sciences University of Melbourne Melbourne 3010 Australia.ORCID https://orcid.org/0000-0001-6469-9592
Ellie H-J ChoBiological Optical Microscopy Platform University of Melbourne Melbourne Australia.ORCID https://orcid.org/0000-0002-2932-1890
T John MartinSt. Vincent's Institute of Medical Research Fitzroy 3065 Australia.ORCID https://orcid.org/0000-0002-8953-1291
Paul GregorevicCentre for Muscle Research, Department of Anatomy and Physiology, School of Biomedical Sciences University of Melbourne Melbourne 3010 Australia.ORCID https://orcid.org/0000-0002-7418-8945
Natalie A SimsSt. Vincent's Institute of Medical Research Fitzroy 3065 Australia.ORCID https://orcid.org/0000-0003-1421-8468
Gordon S LynchCentre for Muscle Research, Department of Anatomy and Physiology, School of Biomedical Sciences University of Melbourne Melbourne 3010 Australia.ORCID https://orcid.org/0000-0001-9220-9810
The University of Melbourne · AUSt Vincents Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of the musculoskeletal system and its maintenance depends on the reciprocal relationship between muscle and bone. The size of skeletal muscles and the forces generated during muscle contraction are potent sources of mechanical stress on the developing skeleton, and they shape bone structure during growth. This is particularly evident in hypermuscular global myostatin (Mstn)-

Indexed as

ANIMAL MODELSBONE MODELING AND REMODELINBONE MORPHOGENETIC PROTEINBONE–MUSCLE INTERACTIONCELL/TISSUE SIGNALING—PARACRINE PATHWAYSMOLECULAR PATHWAYS—REMODELINGPRECLINICAL STUDIESSYSTEMS BIOLOGY—BONE INTERACTORSTRANSFORMING GROWTH FACTOR β

Identifiers

PMID33869993
PMCPMC8046154
OpenAlexW3126889673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.