Evidence map›Paper›PMID 33869988›Full record

ArticleJBMR plus2021

Characterization of Primary Cilia in Osteoblasts Isolated From Patients With ADPKD and CKD.

Renata C Pereira, Berenice Y Gitomer, Michel Chonchol, Peter C Harris, Kathleen J Noche, Isidro B Salusky, Lauren V Albrecht

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Important Role of Polycystin in the Skeletal System.Calcified tissue international · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Autosomal Dominant Polycystic Kidney Disease: Extrarenal Involvement.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Osteocytes and Primary Cilia.Current osteoporosis reports · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Renata C PereiraDepartment of Pediatrics David Geffen School of Medicine at UCL Los Angeles CA USA.
Berenice Y GitomerDepartment of Medicine, Division of Renal Diseases and Hypertension University of Colorado Anschutz Medical Campus Aurora CO USA.
Michel ChoncholDepartment of Medicine, Division of Renal Diseases and Hypertension University of Colorado Anschutz Medical Campus Aurora CO USA.
Peter C HarrisDivision of Nephrology and Hypertension Mayo Clinic Rochester MN USA.
Kathleen J NocheDepartment of Pediatrics David Geffen School of Medicine at UCL Los Angeles CA USA.
Isidro B SaluskyDepartment of Pediatrics David Geffen School of Medicine at UCL Los Angeles CA USA.
Lauren V AlbrechtDepartment of Biological Chemistry David Geffen School of Medicine at UCLA Los Angeles CA USA.ORCID https://orcid.org/0000-0002-3147-8010
University of California, Los Angeles · USUniversity of Colorado Anschutz Medical Campus · USMayo Clinic · US

Funding

Regulation of Bone Mineralization in Renal OsteodystrophyR01DK035423 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SALUSKY, ISIDRO B. · 1986 to 2012
$4.9M
FGF-23 and clinical outcomes in ADPKD patientsR01DK094796 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CHONCHOL, MICHEL BENJAMIN, GITOMER, BERENICE YOLANDE · 2012 to 2016
$2.3M
NIDDK NIH HHS R01 DK035423NIDDK NIH HHS R01 DK094796
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease (CKD) and leads to a specific type of bone disease. The primary cilium is a major cellular organelle implicated in the pathophysiology of ADPKD caused by mutations in polycystin-1 (

Indexed as

AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASEBONECHRONIC KIDNEY DISEASEOSTEOBLASTSPOLYCYSTIC KIDNEY DISEASEPRIMARY CILIA

Identifiers

PMID33869988
PMCPMC8046038
OpenAlexW3123224450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.