Evidence map›Paper›PMID 33869964›Full record

ArticleACS omega2021

Corrosion Behavior and Biocompatibility of Diamond-like Carbon-Coated Zinc: An In Vitro Study.

Feng Peng, Yulin Lin, Dongdong Zhang, Qingdong Ruan, Kaiwei Tang, Mei Li, Xuanyong Liu, Paul K Chu, Yu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Review
  6. Article
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  9. Review
  10. Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Feng PengDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Yulin LinGuangzhou Key Laboratory of Enhanced Recovery after Abdominal Surgery, Department of Orthopedics, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, China.
Dongdong ZhangState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China.
Qingdong RuanDepartment of Physics, Department of Materials Science and Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Kowloon 999077, Hong Kong.
Kaiwei TangDepartment of Physics, Department of Materials Science and Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Kowloon 999077, Hong Kong.
Mei LiDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Xuanyong LiuState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China.
Paul K ChuDepartment of Physics, Department of Materials Science and Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Kowloon 999077, Hong Kong.
Yu ZhangDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the desirable degradation rate and good biocompatibility, zinc (Zn) and Zn alloys are promising biodegradable implant metals in orthopedic and cardiovascular applications. Surface modification, such as deposition of coatings, is frequently implemented to further enhance their biological properties. In this study, diamond-like carbon (DLC) films are deposited on Zn by magnetron sputtering. The DLC films do not change the surface morphology of Zn but alter the hydrophobic properties with a contact angle of approximately 90°. Electrochemical and in vitro immersion tests reveal that the corrosion resistances of the DLC-coated Zn decrease unexpectedly, which is possibly due to galvanic corrosion between the DLC film and Zn substrate. Furthermore, the uncoated and coated Zn samples show hemolysis ratios less than 1%. The cells cultured in the Zn extract exhibit higher viability than those cultured in the extract of the DLC-coated Zn, suggesting that the DLC films decrease the cytocompatibility of Zn. The lower corrosion resistance has little influence on the hemolysis ratio, suggesting that hemolysis is not an obstacle for the design of Zn-based biomaterials. Our results show that the traditional concept of protection with DLC films may not be applicable universally and decreased corrosion resistance and cytocompatibility are actually observed in DLC-coated Zn.

Identifiers

PMID33869964
PMCPMC8047653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.