Evidence map›Paper›PMID 33869911›Full record

ArticleCurrent opinion in physiology2021

Cuneate nucleus: The somatosensory gateway to the brain.

Christopher Versteeg, Raeed H Chowdhury, Lee E Miller

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Subcortical contributions to the sense of body ownership.Brain : a journal of neurology · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christopher VersteegDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern 7 University, Evanston, IL, USA.
Raeed H ChowdhuryDepartment of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 10 Pittsburgh, PA, USA.
Lee E MillerDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern 7 University, Evanston, IL, USA.
Northwestern University · USUniversity of Pittsburgh · US

Funding

Biomimetic Somatosensory Feedback through IntracorticalmicrostimulationR01NS095251 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BENSMAIA, SLIMAN, GRILL, WARREN M. · 2016 to 2020
$3.7M
Probing somatosensory representations in the cuneate nucleus of awake primatesR01NS095162 · NINDS · UNIVERSITY OF CHICAGO · PI BENSMAIA, SLIMAN, MILLER, LEE · 2015 to 2019
$2.5M
Motor Cortical Function During Motor Learning with a Brain-Machine InterfaceF31NS092356 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERICH, MATTHEW GEORGE · 2015 to 2017
$93k
NINDS NIH HHS F31 NS092356NINDS NIH HHS R01 NS095162NINDS NIH HHS R01 NS095251
6 · The paper itself

Abstract

Much remains unknown about the transformation of proprioceptive afferent input from the periphery to the cortex. Until recently, the only recordings from neurons in the cuneate nucleus (CN) were from anesthetized animals. We are beginning to learn more about how the sense of proprioception is transformed as it propagates centrally. Recent recordings from microelectrode arrays chronically implanted in CN have revealed that CN neurons with muscle-like properties have a greater sensitivity to active reaching movements than to passive limb displacement, and we find that these neurons have receptive fields that resemble single muscles. In this review, we focus on the varied uses of proprioceptive input and the possible role of CN in processing this information.

Indexed as

dorsal columnmovementmuscle receptorproprioceptive systemreachingsensorimotor control

Identifiers

PMID33869911
PMCPMC8049169
OpenAlexW3134455692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.