Evidence map›Paper›PMID 33869778›Full record

ArticleOpen medicine (Warsaw, Poland)2021

Knockdown of circ_0003204 alleviates oxidative low-density lipoprotein-induced human umbilical vein endothelial cells injury: Circulating RNAs could explain atherosclerosis disease progression.

Qiuxia Su, Xianhua Dong, Chonghui Tang, Xiaojie Wei, Youguo Hao, Jun Wu

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Qiuxia SuUniversity Healthcare Branch II, The First Affliated Hospital of Xiamen University, Xiamen, China.
Xianhua DongDepartment of Neurosurgery, The First People's Hospital of Jiangxia District, Xiehe, Wuhan, Hubei, China.
Chonghui TangDepartment of Neurosurgery, Cixi Hospital, Wenzhou Medical University, Cixi, Zhejiang, China.
Xiaojie WeiDepartment of Neurosurgery, Cixi Hospital, Wenzhou Medical University, Cixi, Zhejiang, China.
Youguo HaoDepartment of Rehabilitation, Shanghai Putuo People's Hospital, Putuo People's Hospital Affiliated to Tongji University, Shanghai, China.
Jun WuDepartment of Neurology, Central Hospital of Xianyang, No. 78, East People Road, Xianyang 712000, Shanxi, China.
Wenzhou Medical University · CNCentral Hospital of Putuo District · CNFirst Affiliated Hospital of Xiamen University · CNThe First People's Hospital of Jiangxia District · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a serious cardiovascular disease. Circular RNAs (circRNAs) play an important role in the progression of many diseases, including AS. However, the role of circ_0003204 in AS is not clear. Oxidized low-density lipoprotein (ox-LDL)-induced human umbilical vein endothelial cells (HUVECs) were used to construct an AS cell model

Indexed as

AScirc_0003204miR-330-5pNF-κBox-LDLTLR4

Identifiers

PMID33869778
PMCPMC8034243
OpenAlexW3153360755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.