Evidence map›Paper›PMID 33869752›Full record

ArticleLaryngoscope investigative otolaryngology2021

Sarcopenia is associated with blood transfusions in head and neck cancer free flap surgery.

Alexander Joseph Jones, Vincent J Campiti, Mohamedkazim Alwani, Leah J Novinger, Brady Jay Tucker, Andrea Bonetto, Jessica A Yesensky, Michael W Sim, Michael G Moore, Avinash V Mantravadi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  12. Role of sarcopenia on survival and treatment-related toxicity in head and neck cancer: a narrative review of current evidence and future perspectives.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alexander Joseph JonesDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-9219-285X
Vincent J CampitiDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.
Mohamedkazim AlwaniDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-8311-4040
Leah J NovingerDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-9018-7838
Brady Jay TuckerDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-4127-1689
Andrea BonettoDepartment of Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-3235-1871
Jessica A YesenskyDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-1558-9693
Michael W SimDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0001-6571-9452
Michael G MooreDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.
Avinash V MantravadiDepartment of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0002-7971-481X
Indiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if sarcopenia is a predictor of blood transfusion requirements in head and neck cancer free flap reconstruction (HNCFFR).

methodsA single-institution, retrospective review was performed of HNCFFR patients with preoperative abdominal imaging from 2014 to 2019. Demographics, comorbidities (modified Charlson Comorbidity Index [mCCI]), skeletal muscle index (cm

resultsEighty (33.5%), 66 (27.6%), and 110 (46.0%) of n = 239 total patients received an intraoperative, postoperative, or any perioperative blood transfusion, respectively. Sixty-two (25.9%) patients had sarcopenia. Patients receiving intraoperative transfusions had older age (

conclusionSarcopenia is associated with increased blood transfusions in HNCFFR. Patients should be counseled preoperatively on the associated risks, and the increased blood product requirement should be accounted in resource-limited scenarios. LEVEL OF EVIDENCE: 4.

Indexed as

blood transfusionfree flap reconstructionhead and neck cancersarcopeniaskeletal muscle index

Identifiers

PMID33869752
PMCPMC8035950
OpenAlexW3127141199

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.