Evidence map›Paper›PMID 33869639›Full record

ArticleJournal of immunology research2021

Antiviral Efficacy of the Anesthetic Propofol against Dengue Virus Infection and Cellular Inflammation.

Ting-Jing Shen, Chia-Ling Chen, Ming-Kai Jhan, Po-Chun Tseng, Rahmat Dani Satria, Chung-Hsi Hsing, Chiou-Feng Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ting-Jing ShenGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID https://orcid.org/0000-0002-1714-0048
Chia-Ling ChenSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Ming-Kai JhanGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Po-Chun TsengDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Rahmat Dani SatriaDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chung-Hsi HsingDepartment of Medical Research, Chi-Mei Medical Center, Tainan 710, Taiwan.ORCID https://orcid.org/0000-0002-6091-5371
Chiou-Feng LinGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID https://orcid.org/0000-0003-4396-6086
Taipei Medical University · TWChi Mei Medical Center · TWUniversitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propofol, 2,6-diisopropylphenol, is a short-acting intravenous sedative agent used in adults and children. Current studies show its various antimicrobial as well as anti-inflammatory effects. Dengue virus (DENV) is an emerging infectious pathogen transmitted by mosquitoes that causes mild dengue fever and progressive severe dengue diseases. In the absence of safe vaccines and antiviral agents, adjuvant treatments and supportive care are generally administered. This study investigated the antiviral effects of propofol against DENV infection and cellular inflammation by using an

Indexed as

AnestheticsAnimalsAnti-Inflammatory AgentsAntiviral AgentsCell LineDengueDengue VirusHumansImmunity, CellularInflammationInterferon-gammaPropofolSignal TransductionTumor Necrosis Factor-alphaVirus ReplicationAnestheticsAnti-Inflammatory AgentsAntiviral AgentsInterferon-gammaPropofolTumor Necrosis Factor-alpha

Identifiers

PMID33869639
PMCPMC8032536
OpenAlexW3142099550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.