Evidence map›Paper›PMID 33869320›Full record

ArticleFrontiers in veterinary science2021

Histopathological Classification of Canine Cutaneous Round Cell Tumors Using Deep Learning: A Multi-Center Study.

Massimo Salvi, Filippo Molinari, Selina Iussich, Luisa Vera Muscatello, Luca Pazzini, Silvia Benali, Barbara Banco, Francesca Abramo, Raffaella De Maria, Luca Aresu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  7. Cutaneous plasmacytoma with Mott cell differentiation in a dog.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Massimo SalviPoliToBIOMed Lab, Biolab, Department of Electronics and Telecommunications, Politecnico di Torino, Turin, Italy.
Filippo MolinariPoliToBIOMed Lab, Biolab, Department of Electronics and Telecommunications, Politecnico di Torino, Turin, Italy.
Selina IussichDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Luisa Vera MuscatelloDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Luca PazziniMyLav-Laboratorio La Vallonea, Milan, Italy.
Silvia BenaliMyLav-Laboratorio La Vallonea, Milan, Italy.
Barbara BancoMyLav-Laboratorio La Vallonea, Milan, Italy.
Francesca AbramoDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.
Raffaella De MariaDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Luca AresuDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
University of Turin · ITPolytechnic University of Turin · ITUniversity of Bologna · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine cutaneous round cell tumors (RCT) represent one of the routine diagnostic challenges for veterinary pathologists. Computer-aided approaches are developed to overcome these restrictions and to increase accuracy and consistency of diagnosis. These systems are also of high benefit reducing errors when a large number of cases are screened daily. In this study we describe ARCTA (Automated Round Cell Tumors Assessment), a fully automated algorithm for cutaneous RCT classification and mast cell tumors grading in canine histopathological images. ARCTA employs a deep learning strategy and was developed on 416 RCT images and 213 mast cell tumors images. In the test set, our algorithm exhibited an excellent classification performance in both RCT classification (accuracy: 91.66%) and mast cell tumors grading (accuracy: 100%). Misdiagnoses were encountered for histiocytomas in the train set and for melanomas in the test set. For mast cell tumors the reduction of a grade was observed in the train set, but not in the test set. To the best of our knowledge, the proposed model is the first fully automated algorithm in histological images specifically developed for veterinary medicine. Being very fast (average computational time 2.63 s), this algorithm paves the way for an automated and effective evaluation of canine tumors.

Indexed as

computer-aided image analysiscutaneous round cell tumorsdeep learningdigital pathologydogmast cell tumors

Identifiers

PMID33869320
PMCPMC8044886
OpenAlexW3142364075

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.