Evidence map›Paper›PMID 33869094›Full record

ArticleEuropean journal of case reports in internal medicine2021

COVID-19-Induced Hyperleucocytosis in Chronic Lymphocytic Leukaemia.

Balraj Singh, Sarah Ayad, Parminder Kaur, Ro-Jay Reid, Sachin Gupta, Michael Maroules

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Unexpected CD5Journal of clinical medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Balraj SinghSaint Joseph's University Medical Center, Peterson, NJ, USA.
Sarah AyadSaint Joseph's University Medical Center, Peterson, NJ, USA.
Parminder KaurSaint Joseph's University Medical Center, Peterson, NJ, USA.
Ro-Jay ReidSaint Joseph's University Medical Center, Peterson, NJ, USA.
Sachin GuptaSaint Joseph's University Medical Center, Peterson, NJ, USA.
Michael MaroulesSaint Joseph's University Medical Center, Peterson, NJ, USA.
St. Joseph’s University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for the current global pandemic, coronavirus disease 2019 (COVID-19). COVID-19 usually presents with respiratory symptoms but can affect multiple organ systems. A wide spectrum of complications can occur depending upon the comorbidities of patients. There is limited literature available regarding the presentation and outcome of COVID-19 in chronic lymphocytic leukaemia (CLL) patients. We report 2 cases of COVID-19-induced hyperleucocytosis (WBC count >100,000/μl) in CLL patients. LEARNING POINTS: Lymphopenia has been associated with severe disease and is a poor prognostic factor in COVID-19 infected patients; however, our cases show COVID-19-induced hyperleucocytosis (WBC count >100,000/μl)/lymphocytosis in CLL patients.Prior reports suggest that ibrutinib may have a protective effect against COVID-19 by decreasing inflammation and preventing progression to ARDS.

Indexed as

chronic lymphocytic leukaemiaCLLCOVID-19leucocytosislymphocytosislymphopeniaSARS-CoV-2

Identifiers

PMID33869094
PMCPMC8046275
OpenAlexW3155581821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.