Evidence map›Paper›PMID 33869051›Full record

ArticleFrontiers in oncology2021

LINC00941 Promotes Progression of Non-Small Cell Lung Cancer by Sponging miR-877-3p to Regulate VEGFA Expression.

Min-Huan Ren, Si Chen, Liang-Ge Wang, Wen-Xiu Rui, Pei Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

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  7. lncHUB2: aggregated and inferred knowledge about human and mouse lncRNAs.Database : the journal of biological databases and curation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Min-Huan RenDepartment of Respiratory Disease, Taikang Xianlin Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.
Si ChenDepartment of Respiratory Disease, Taikang Xianlin Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.
Liang-Ge WangDepartment of Respiratory Disease, Taikang Xianlin Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.
Wen-Xiu RuiDepartment of Respiratory Disease, Taikang Xianlin Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.
Pei LiDepartment of Infectious Diseases, Affiliated Hospital 2 of Nantong University, Nantong, China.
Nanjing Drum Tower Hospital · CNAffiliated Hospital of Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) play critical roles in carcinoma occurrence and metastasis. LINC00941 has been found to mediate the development of gastric cancer, and LINC00941 was negatively associated with the longer overall survival of lung adenocarcinoma patients. Herein, our aim was to investigate the effects and mechanisms of LINC00941 in NSCLC progression. Microarray was used to identify the change lncRNAs in NSCLC, LINC00941 was found to increase in tumor tissues and patients' plasma. Knockdown of LINC00941 didn't modulate the proliferation of NSCLC cells, but inhibition of LINC00941 in NSCLC cells suppressed the angiogenesis ability of human umbilical vein endothelial cells (HUVECs). Moreover, LINC00941 promoted tumorigenesis

Indexed as

angiogenesisLINC00941non-small cell lung cancer (NSCLC)tumorigenesisVEGFA

Identifiers

PMID33869051
PMCPMC8044452
OpenAlexW3150496333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.