Evidence map›Paper›PMID 33869048›Full record

ReviewFrontiers in oncology2021

Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis.

Chunyu Zhang, Jiao Hu, Huihuang Li, Hongzhi Ma, Belaydi Othmane, Wenbiao Ren, Zhenglin Yi, Dongxu Qiu, Zhenyu Ou, Jinbo Chen and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. THAP7-AS1 orchestrates IGF2BP3-mAmerican journal of cancer research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Chunyu ZhangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Jiao HuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Huihuang LiDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Hongzhi MaDepartment of Radiation Oncology, Hunan Cancer Hospital, Central South University, Changsha, China.
Belaydi OthmaneDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Wenbiao RenDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Zhenglin YiDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Dongxu QiuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Zhenyu OuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Jinbo ChenDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Xiongbing ZuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CNHunan Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer is one of the leading causes of cancer deaths worldwide. Early detection of lymph node metastasis of bladder cancer is essential to improve patients' prognosis and overall survival. Current diagnostic methods are limited, so there is an urgent need for new specific biomarkers. Non-coding RNA and m6A have recently been reported to be abnormally expressed in bladder cancer related to lymph node metastasis. In this review, we tried to summarize the latest knowledge about biomarkers, which predict lymph node metastasis in bladder cancer and their mechanisms. In particular, we paid attention to the impact of non-coding RNA on lymphatic metastasis of bladder cancer and its specific molecular mechanisms, as well as some prediction models based on imaging, pathology, and biomolecules, in an effort to find more accurate diagnostic methods for future clinical application.

Indexed as

biomarkersbladder cancerlymph node metastasisoncogenestumor suppressor genes

Identifiers

PMID33869048
PMCPMC8044933
OpenAlexW3138591331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.