Evidence map›Paper›PMID 33868963›Full record

ArticleToxicology reports2021

Myorelaxation, respiratory depression and electrocardiographic changes caused by the administration of extract of açai (

Nilton Akio Muto, Moisés Hamoy, David Cristian Rodrigues Lucas, Bruno Brito Teixeira, Adrielle Felicia Santos Almeida, Thamires de Castro Navegantes, Vaniza Sheila de Sousa Ferreira de Sá, Brenda Pinto de Moraes, João Paulo do Vale Medeiros, Yasmin Amorim Dos Santos and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Antiarrhythmic Effects of Supercritical Extract ofPlants (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Açaí (Nutrients · 2023
    Review
  6. Article
  7. Extract ofFrontiers in cellular neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Nilton Akio MutoUFPA & Centre for Valorization of Amazonian Bioactive Compounds (CVACBA), Belém, Pará, Brazil.
Moisés HamoyLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
David Cristian Rodrigues LucasUFPA & Centre for Valorization of Amazonian Bioactive Compounds (CVACBA), Belém, Pará, Brazil.
Bruno Brito TeixeiraUFPA & Centre for Valorization of Amazonian Bioactive Compounds (CVACBA), Belém, Pará, Brazil.
Adrielle Felicia Santos AlmeidaUFPA & Centre for Valorization of Amazonian Bioactive Compounds (CVACBA), Belém, Pará, Brazil.
Thamires de Castro NavegantesLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
Vaniza Sheila de Sousa Ferreira de SáLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
Brenda Pinto de MoraesLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
João Paulo do Vale MedeirosLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
Yasmin Amorim Dos SantosLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
Claúdia Quintino da RochaLaboratory of Chemistry of Natural Products, UFMA, Brazil.
Vanessa Joia de MelloLaboratory of Pharmacology and Toxicology of Natural Products, ICB-UFPA, Brazil.
Hervé RogezUFPA & Centre for Valorization of Amazonian Bioactive Compounds (CVACBA), Belém, Pará, Brazil.
Amazon Research Foundation · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological and pharmacological properties of natural polyphenols of the extract of

Indexed as

ACB, abdominal-costal breathingCNS, Central Nervous SystemDMACA, p-dimethylaminocinnamaldehydeDZP, diazepamECGEEOS, extract of E. oleracea stoneEMGEMG, electromyographicEMGs, electromyographsESI-IT-MS, Electrospray ionization Ion-Trap Mass spectrometryEuterpe oleraceaGABAA, γ-aminobutyric acid type AHPLC, High Performance Liquid Chromatographymg CAE/g DE, milligrams of catechin equivalents per gram of dried extractmg CE/g DE, milligrams of cyanidin equivalents per gram of dried extractmg GAE/g DE, milligrams of gallic acid equivalents per gram of dried extractmg MRE/g DE, miligrams of myricetin-3-O-α-l-rhamnopyranoside equivalents per gram of dried extractMyorelaxantRC, Respiratory ControlRD, respiratory depressionRPR, Rhythmic and Profound RespirationSedative

Identifiers

PMID33868963
PMCPMC8044785
OpenAlexW3150380196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.