Evidence map›Paper›PMID 33868894›Full record

ReviewIn silico pharmacology2021

Topoisomerase II as a target for repurposed antibiotics in

Ashwini Khanderao Jadhav, Sankunny Mohan Karuppayil

Open access · greenAbstract readReview
In one paragraph

Review in In silico pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Synthesis (ACS omega · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ashwini Khanderao JadhavDepartment of Stem Cell and Regenerative Medicine, Centre for Interdisciplinary Research, DY Patil Education Society (Deemed to be University), (NAAC Re Accredited with 'A' Grade), Kolhapur, Maharashtra 416006 India.
Sankunny Mohan KaruppayilDepartment of Stem Cell and Regenerative Medicine, Centre for Interdisciplinary Research, DY Patil Education Society (Deemed to be University), (NAAC Re Accredited with 'A' Grade), Kolhapur, Maharashtra 416006 India.
D.Y. Patil Education Society · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluoroquinolines, the widely used antibacterial antibiotics, have been shown to interact with human DNA topoisomerases supporting their use as repurposed cancer drugs in humans. In this communication molecular docking of eleven Fluoroquinolines against predicted structure of

Indexed as

Candida albicansDNA Topoisomerase IIFluoroquinolinesMolecular dockingRepurposing

Identifiers

PMID33868894
PMCPMC7997935
OpenAlexW3155368903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.