Evidence map›Paper›PMID 33868783›Full record

ArticleMolecular therapy. Nucleic acids2021

MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660.

Hua-Jian Shan, Lun-Qing Zhu, Chen Yao, Zhi-Qing Zhang, Yuan-Yuan Liu, Qin Jiang, Xiao-Zhong Zhou, Xiao-Dong Wang, Cong Cao

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

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  18. G protein inhibitory α subunit 2 is a molecular oncotarget of human glioma.International journal of biological sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hua-Jian ShanDepartment of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215003, China.
Lun-Qing ZhuDepartment of Pediatric Orthopedics, The Children's Hospital of Soochow University, Suzhou 215100, China.
Chen YaoDepartment of Orthopedics, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of TCM, Nanjing, China.
Zhi-Qing ZhangJiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou 215123, China.
Yuan-Yuan LiuDepartment of Radiotherapy and Oncology, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, China.
Qin JiangThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, China.
Xiao-Zhong ZhouDepartment of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215003, China.
Xiao-Dong WangDepartment of Pediatric Orthopedics, The Children's Hospital of Soochow University, Suzhou 215100, China.
Cong CaoJiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou 215123, China.
Soochow University · CNJiangsu University · CNNanjing Medical University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is the most common primary bone malignancy in the adolescent population. MAFG (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G) forms a heterodimer with Nrf2 (NF-E2-related factor 2), binding to antioxidant response element (ARE), which is required for Nrf2 signaling activation. We found that

Indexed as

MAFGmiRNA-4660molecularly targeted therapyNrf2 signalingosteosarcoma

Identifiers

PMID33868783
PMCPMC8039776
OpenAlexW3137149380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.