A Nonfunctioning Pituitary Macroadenoma Presenting as Cyclical Vomiting and Severe Hyponatremia in a Young Female.

Dinuka S Warapitiya, Dimuthu Muthukuda, W A H P Sanjeewa, Kushalee Poornima Jayawickreme, Shyama Subasinghe

Open access · goldAbstract readCase Reports

In one paragraph

Article in Case reports in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.1field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dinuka S WarapitiyaPostgraduate Institute of Medicine, University of Colombo, Colombo, Sri Lanka.ORCID https://orcid.org/0000-0003-2169-0760

Dimuthu MuthukudaDiabetes and Endocrinology Unit, Sri Jayewardenepura General Hospital, Nugegoda, Colombo, Sri Lanka.

W A H P SanjeewaPostgraduate Institute of Medicine, University of Colombo, Colombo, Sri Lanka.ORCID https://orcid.org/0000-0002-4812-5852

Kushalee Poornima JayawickremePostgraduate Institute of Medicine, University of Colombo, Colombo, Sri Lanka.ORCID https://orcid.org/0000-0001-9503-2854

Shyama SubasingheSri Jayewardenepura General Hospital, Nugegoda, Colombo, Sri Lanka.

University of Colombo · LKUniversity of Sri Jayewardenepura · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecurrent vomiting is a commonly overlooked debilitating symptom which causes significant impact on the quality of life. There are several causes for vomiting, ranging from commonly known causes to rare causes. Nonfunctioning pituitary macroadenomas generally present with visual disturbances, headache, and symptoms due to anterior pituitary hormone deficiencies. This case report is about an atypical presentation of a nonfunctioning pituitary macroadenoma in which the patient presented with cyclical vomiting with severe hyponatremia.

conclusionThere can be multiple overlapping aetiologies for every observed symptom, sign, and abnormal investigation finding. Therefore, aetiological diagnosis is challenging, especially in the presence of an atypical clinical presentation. Cyclical vomiting and severe hyponatremia are atypical presentations of nonfunctioning pituitary macroadenomas.

Identifiers

PMID33868733

DOI10.1155/2021/5570539

PMCPMC8032522

OpenAlexW3150655080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.