ArticleBioelectronics in medicine2019
Adding wisdom to 'smart' bioelectronic systems: a design framework for physiologic control including practical examples.
Article in Bioelectronics in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- EEG-based hypoglycemia detection in Type 1 Diabetes: Proof-of-concept study.Frontiers in human neuroscience · 2026Article
- Deep brain stimulation-induced local evoked potentials outperform spectral features in spatial and clinical STN mapping.Journal of neural engineering · 2025Article
- The Design of Brainstem Interfaces: Characterisation of Physiological Artefacts and Implications for Closed-loop Algorithms.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2023Article
- Article
- Diurnal modulation of subthalamic beta oscillatory power in Parkinson's disease patients during deep brain stimulation.NPJ Parkinson's disease · 2022Article
- DyNeuMo Mk-1: Design and pilot validation of an investigational motion-adaptive neurostimulator with integrated chronotherapy.Experimental neurology · 2022Article
- Physiologically informed neuromodulation.Journal of the neurological sciences · 2022Article
- Workshops of the Eighth International Brain-Computer Interface Meeting: BCIs: The Next Frontier.Brain computer interfaces (Abingdon, England) · 2022Article
- Methods for Lowering the Power Consumption of OS-Based Adaptive Deep Brain Stimulation Controllers.Sensors (Basel, Switzerland) · 2021Article
- Controlling Clinical States Governed by Different Temporal Dynamics With Closed-Loop Deep Brain Stimulation: A Principled Framework.Frontiers in neuroscience · 2021Article
- Sleep-Aware Adaptive Deep Brain Stimulation Control: Chronic Use at Home With Dual Independent Linear Discriminate Detectors.Frontiers in neuroscience · 2021Article
- Case Report: Embedding "Digital Chronotherapy" Into Medical Devices-A Canine Validation for Controlling Status Epilepticus Through Multi-Scale Rhythmic Brain Stimulation.Frontiers in neuroscience · 2021Article
- Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor.Science translational medicine · 2020Article
- DyNeuMo Mk-2: An Investigational Circadian-Locked Neuromodulator with Responsive Stimulation for Applied Chronobiology.Conference proceedings. IEEE International Conference on Systems, Man, and Cybernetics · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
This perspective provides an overview of how risk can be effectively considered in physiological control loops that strive for semi-to-fully automated operation. The perspective first introduces the motivation, user needs and framework for the design of a physiological closed-loop controller. Then, we discuss specific risk areas and use examples from historical medical devices to illustrate the key concepts. Finally, we provide a design overview of an adaptive bidirectional brain-machine interface, currently undergoing human clinical studies, to synthesize the design principles in an exemplar application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.