Evidence map›Paper›PMID 33868707›Full record

ArticleBMJ open sport & exercise medicine2021

Impact of chronic Achilles tendinopathy on health-related quality of life, work performance, healthcare utilisation and costs.

Tjerk S O Sleeswijk Visser, Arco C van der Vlist, Robert F van Oosterom, Peter van Veldhoven, Jan A N Verhaar, Robert-Jan de Vos

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMJ open sport & exercise medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 6 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02996409 phase4completednot on this map

The Value of a High-Volume Image-Guided Injection in Chronic Midportion Achilles Tendinopathy: a Double-blind, Randomized, Placebo-controlled Clinical Trial

TypeinterventionalSponsorErasmus Medical CenterRan2016 to 2019Enrolled80ConditionsTendinopathy, Achilles Tendon Pain, Injection Site FibrosisArmsHVIGI, LVIGI, Progressive exercise program
NCT05659134 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparison of Alfredson Eccentric and Silbernagel Concentric-eccentric Therapeutical Protocol in Competitive Athletes With Chronic Achilles Tendinopathy

TypeinterventionalSponsorCharles University, Czech RepublicRan2022 to 2024Enrolled40ConditionsAchilles Tendinopathy, Tendon Injuries, Tendon Thickening, Pain, ChronicArmsAlfredson protocol, Silbernagel protocol
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 6 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
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  6. The impact of nutrition on tendon health and tendinopathy: a systematic review.Journal of the International Society of Sports Nutrition · 2022
    Pooled it
  7. Trial
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  13. Article
  14. Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  15. Relationship Between Structure and Age in Healthy Achilles Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  16. Achilles tendinopathy.Nature reviews. Disease primers · 2025
    Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tjerk S O Sleeswijk VisserDepartment of Orthopedic Surgery and Sports Medicine, Erasmus MC University Medical Centre, Rotterdam, Netherlands.ORCID 0000-0002-4483-1936
Arco C van der VlistDepartment of Orthopedic Surgery and Sports Medicine, Erasmus MC University Medical Centre, Rotterdam, Netherlands.
Robert F van OosteromDepartment of Sports Medicine, Haaglanden Medical Centre, Leidschendam, The Netherlands.
Peter van VeldhovenDepartment of Sports Medicine, Haaglanden Medical Centre, Leidschendam, The Netherlands.
Jan A N VerhaarDepartment of Orthopedic Surgery and Sports Medicine, Erasmus MC University Medical Centre, Rotterdam, Netherlands.
Robert-Jan de VosDepartment of Orthopedic Surgery and Sports Medicine, Erasmus MC University Medical Centre, Rotterdam, Netherlands.
Erasmus MC · NLMedisch Centrum Haaglanden · NLLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the impact of Achilles tendinopathy (AT) on quality of life (QoL), work performance, healthcare utilisation and costs in adults with conservatively treated chronic midportion AT.

methodsThis cross-sectional survey-based study included 80 patients and took place in a sports medicine department of a large regional hospital in the Netherlands. Data were collected before any intervention was given. Primary outcome was the EuroQol questionnaire (EQ-5D). The EQ-5D expresses the percentage of moderate/major problems on the domains self-care, anxiety/depression, mobility, usual activities and pain/discomfort. Secondary outcomes were the number of previous healthcare visits, work performance during the period of symptoms and estimated annual direct medical and indirect costs per patient as a result of AT.

resultsAll 80 patients completed the questionnaires. The EQ-5D scores were low for the domains self-care (1%) and anxiety/depression (20%), and high for the domains mobility (66%), usual activities (50%) and pain/discomfort (89%). Patients with AT mainly reported an impact on work productivity (38%). Work absenteeism due to AT was present in 9%. The total median (IQR) number of annual healthcare visits was 9 (3-11). The total mean (SD) estimated annual costs were €840 (1420) per patient with AT (mean (SD) US$991 (1675)).

conclusionsThis study shows the large impact of AT on QoL and work productivity. This study also provides new information about the socioeconomic impact of AT, which emphasises that this common and longstanding disease causes substantial costs. These findings stress the need for optimised treatment and improved preventive interventions for AT. TRIAL REGISTRATION NUMBER: NCT02996409.

Indexed as

Achilleseconomicsquality of lifesociologytendinosis

Identifiers

PMID33868707
PMCPMC8006822
OpenAlexW3141976296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.