Evidence map›Paper›PMID 33868684›Full record

ArticleAnnals of medicine and surgery (2012)2021

Primary cervical glioblastoma multiforme as a presentation of constitutional mismatch repair deficiency: Case report and literature review.

Sultan M Jarrar, Suleiman S Daoud, Omar F Jbarah, Iyad S Albustami, Moh'd Alamin Daise

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pediatric-type high-grade glioma of the spinal cord in the molecular era: institutional case series and updated systematic review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sultan M JarrarDepartment of Clinical Neuroscience, Faculty of Medicine, Jordan University of Science & Technology, PO Box 3030, Zip Code 22110, Irbid, Jordan.
Suleiman S DaoudDepartment of Clinical Neuroscience, Faculty of Medicine, Jordan University of Science & Technology, PO Box 3030, Zip Code 22110, Irbid, Jordan.
Omar F JbarahDepartment of Clinical Neuroscience, Jordan University of Science & Technology, PO Box 3030, Zip Code 22110, Irbid, Jordan.
Iyad S AlbustamiJordan University of Science & Technology, PO Box 3030, Zip Code 22110, Irbid, Jordan.
Moh'd Alamin DaiseJordan University of Science & Technology, PO Box 3030, Zip Code 22110, Irbid, Jordan.
Jordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and importancePrimary Glioblastoma Multiforme(GBM) of cervical spinal cord represent an extremely rare type of tumors in the pediatric age group. Constitutional mismatch repair deficiency (CMMRD) patients are known to develop uni- or multiple synchronous-high grade gliomas in the brain. CASE PRESENTATION: The authors report a 23 month old child presented with bilateral upper limb weakness for 7 days with imaging evidence of intramedullary mass lesion that extends from the level of the C3 to C7. The patient underwent excisional biopsy from C3 to C7 and laminoplasty. Immunohistology confirmed primary cervical GBM. CLINICAL DISCUSSION: Constitutional mismatch repair deficiency is cancer tendent syndrome associated with broad spectrum of malignancies. Screening for CMMRD is not a daily practice in oncology and thus prevalence might be underestimated. To authors' knowledge, no prior primary cervical GBM in CMMRD syndrome.

conclusionThis report highlights the challenges of CMMRD polymorphic presentations, diagnosis, complications, management and surveillance.

Indexed as

Constitutional mismatch repair deficiencyGlioblastoma multiformeHigh-grade gliomaIntramedullary spinal cord tumorSpine

Identifiers

PMID33868684
PMCPMC8040124
OpenAlexW3141793542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.