Evidence map›Paper›PMID 33868587›Full record

ArticleOncotarget2021

[

Joline F Roze, Hannah S van Meurs, Glen R Monroe, Wouter B Veldhuis, Luc R C W van Lonkhuijzen, Roel J Bennink, Jolijn W Groeneweg, Petronella O Witteveen, Geertruida N Jonges, Ronald P Zweemer and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Feasibility ofVeterinary medicine and science · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Joline F RozeDepartment of Gynecological Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Hannah S van MeursDepartment of Gynecological Oncology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Glen R MonroeDepartment of Gynecological Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Wouter B VeldhuisDepartment of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Luc R C W van LonkhuijzenDepartment of Gynecological Oncology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Roel J BenninkDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Jolijn W GroenewegDepartment of Gynecological Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Petronella O WitteveenDepartment of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Geertruida N JongesDepartment of Pathology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Ronald P ZweemerDepartment of Gynecological Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Arthur J A T BraatDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Utrecht University · NLAmsterdam University Medical Centers · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdult granulosa cell tumors (AGCTs) of the ovary represent a rare malignancy in which timing and choice of treatment is a clinical challenge. This study investigates the value of FDG-PET/CT and FES-PET/CT in monitoring recurrent AGCTs and assessing eligibility for anti-hormonal treatment. MATERIALS AND

methodsWe evaluated 22 PET/CTs from recurrent AGCT patients to determine tumor FDG (

resultsQualitative assessment showed low-to-moderate FDG uptake in most patients (14/16), and intense uptake in 2/16. One patient with intense tumor FDG uptake had a high mitotic rate (18 per 2 mm

conclusionsThis study shows that in AGCTs, FDG uptake is limited and therefore FDG-PET/CT is not advised. FES-PET/CT may be useful to non-invasively capture the estrogen receptor expression of separate tumor lesions and thus assess the potential eligibility for hormone treatment in AGCT patients.

Indexed as

18F-fluoro-deoxyglucose (18F-FDG)18F-fluoroestradiol (18F-FES)granulosa cell tumors (GCTs)hormone receptorspositron emission tomography (PET)

Identifiers

PMID33868587
PMCPMC8021033
OpenAlexW3140042792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.