Evidence map›Paper›PMID 33868488›Full record

ArticleOncology letters2021

Excision repair cross-complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence.

Yen-Yun Wang, Pen-Tzu Fang, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang, Shyng-Shiou F Yuan

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. The oncogenome of the domestic cat.Science (New York, N.Y.) · 2026
    Article
  2. Genetic signatures ofOncology research · 2025
    Article
  3. A multimodal approach for establishingFrontiers in pharmacology · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yen-Yun WangSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807377, Taiwan, R.O.C.
Pen-Tzu FangDepartment of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung 807377, Taiwan, R.O.C.
Chang-Wei SuSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807377, Taiwan, R.O.C.
Yuk-Kwan ChenSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807377, Taiwan, R.O.C.
Joh-Jong HuangDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807377, Taiwan, R.O.C.
Ming-Yii HuangCenter for Cancer Research, Kaohsiung Medical University, Kaohsiung 807377, Taiwan, R.O.C.
Shyng-Shiou F YuanTranslational Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807377, Taiwan, R.O.C.
Kaohsiung Medical University · TW

Funding

Dichotomous Effects of MT1-MMP on Adipose Tissue RemodelingR01DK109001 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SUN, KAI · 2017 to 2021
$2.0M
CENTROSOME DYSFUNCTION IN POLYCYSTIC KIDNEY DISEASER01DK108005 · NIDDK · WASHINGTON UNIVERSITY · PI MAHJOUB, MOHAMED REZA · 2016 to 2020
$1.7M
NIDDK NIH HHS R01 DK108005NIDDK NIH HHS R01 DK109001
6 · The paper itself

Abstract

Oral cancer is the fourth most common type of cancer among males in Taiwan, and the prognosis for patients with advanced-stage oral squamous cell carcinoma (OSCC) remains poor. The present study investigated the prognostic value of three DNA repair genes, namely excision repair cross-complementing group 1 (ERCC1), ERCC2 and X-ray repair cross-complementing group 1 (XRCC1) in OSCC. The protein expression levels of XRCC1, ERCC1 and ERCC2 in oral cell lines were analyzed via western blotting and immunohistochemistry using samples from 98 patients with biopsy-proven OSCC, while the χ

Indexed as

DNA repairexcision repair cross-complementing group 1excision repair cross-complementing group 2oral squamous cell carcinomaX-ray repair cross-complementing group 1

Identifiers

PMID33868488
PMCPMC8045162
OpenAlexW3149564280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.