Evidence map›Paper›PMID 33868363›Full record

ArticleFrontiers in genetics2021

Screening for Combination Cancer Therapies With Dynamic Fuzzy Modeling and Multi-Objective Optimization.

Simone Spolaor, Martijn Scheve, Murat Firat, Paolo Cazzaniga, Daniela Besozzi, Marco S Nobile

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Simone SpolaorDepartment of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy.
Martijn ScheveDepartment of Industrial Engineering & Innovation Sciences, Eindhoven University of Technology, Eindhoven, Netherlands.
Murat FiratDepartment of Industrial Engineering & Innovation Sciences, Eindhoven University of Technology, Eindhoven, Netherlands.
Paolo CazzanigaDepartment of Human and Social Sciences, University of Bergamo, Bergamo, Italy.
Daniela BesozziDepartment of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy.
Marco S NobileDepartment of Industrial Engineering & Innovation Sciences, Eindhoven University of Technology, Eindhoven, Netherlands.
Eindhoven University of Technology · NLUniversity of Milano-Bicocca · ITUniversity of Bergamo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination therapies proved to be a valuable strategy in the fight against cancer, thanks to their increased efficacy in inducing tumor cell death and in reducing tumor growth, metastatic potential, and the risk of developing drug resistance. The identification of effective combinations of drug targets generally relies on costly and time consuming processes based on

Indexed as

cancercombination chemotherapyfuzzy modelingglobal optimizationmulti-objective optimizationtherapeutic targets

Identifiers

PMID33868363
PMCPMC8044361
OpenAlexW3140318448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.