Evidence map›Paper›PMID 33868252›Full record

ArticleFrontiers in immunology2021

NOX2 Deficiency Permits Sustained Survival of

Bettina Tosetti, Beate Ward, Daniela Grumme, Marc Herb, Michael Schramm, Olaf Utermöhlen, Lukas C Heukamp, Martin Krönke, Oleg Krut

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Bettina TosettiInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Beate WardInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Daniela GrummeInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Marc HerbInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Michael SchrammInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Olaf UtermöhlenInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Lukas C HeukampInstitute for Hematopathology Hamburg, Hamburg, Germany.
Martin KrönkeInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Oleg KrutPaul-Ehrlich-Institut, Langen, Germany.
Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEUniversity of Cologne · DEInstitut für Hämatopathologie Hamburg · DEPaul Ehrlich Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the crucial role of professional phagocytes for the clearance of

Indexed as

Microbial ViabilitySeverity of Illness IndexAnimalsFemaleGene DeletionMacrophagesMiceMice, Inbred C57BLNADPH Oxidase 2Reactive Oxygen SpeciesStaphylococcal InfectionsStaphylococcus aureusCybb protein, mouseNADPH Oxidase 2Reactive Oxygen Speciesantibiotic treatmentchronic granulomatous diseasemacrophagesreactive oxygen speciessepsis modelStaphylococcus aureus

Identifiers

PMID33868252
PMCPMC8044967
OpenAlexW3136771322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.