Evidence map›Paper›PMID 33868187›Full record

ArticleFrontiers in microbiology2021

Analysis of Selection Methods to Develop Novel Phage Therapy Cocktails Against Antimicrobial Resistant Clinical Isolates of Bacteria.

Melissa E K Haines, Francesca E Hodges, Janet Y Nale, Jennifer Mahony, Douwe van Sinderen, Joanna Kaczorowska, Bandar Alrashid, Mahmuda Akter, Nathan Brown, Dominic Sauvageau and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Development andMicrobiology spectrum · 2026
    Article
  3. Article
  4. Article
  5. Isolation and characterization of broad-rangeMicrobiology (Reading, England) · 2026
    Article
  6. Review
  7. Review
  8. AFrontiers in microbiology · 2026
    Article
  9. Review
  10. Isolation and characterization of lytic bacteriophages against Staphylococcus aureus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Quantifying phage infectivity from characteristics of bacterial population dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Phage-based biocontrol ofFrontiers in microbiology · 2025
    Article
  19. Systematic bacteriophage selection for the lysis of multipleFrontiers in cellular and infection microbiology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 7 countries.

Melissa E K HainesDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Francesca E HodgesDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Janet Y NaleDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Jennifer MahonySchool of Microbiology and APC Microbiome Ireland, University College Cork, Cork, Ireland.
Douwe van SinderenSchool of Microbiology and APC Microbiome Ireland, University College Cork, Cork, Ireland.
Joanna KaczorowskaSchool of Microbiology and APC Microbiome Ireland, University College Cork, Cork, Ireland.
Bandar AlrashidDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Mahmuda AkterInternational Centre for Diarrheal Diseases Research, Dhaka, Bangladesh.
Nathan BrownDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Dominic SauvageauDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.
Thomas Sicheritz-PonténSection for Evolutionary Genomics, The GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anisha M ThankiDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Andrew D MillardDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Edouard E GalyovDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Martha R J ClokieDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
University of Leicester · GBUniversity College Cork · IEInternational Centre for Diarrhoeal Disease Research · BDKing Faisal Specialist Hospital & Research Centre · SAUniversity of Alberta · CAUniversity of Copenhagen · DK

Funding

Medical Research Council MR/L015080/1Wellcome Trust
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a major problem globally. The main bacterial organisms associated with urinary tract infection (UTI) associated sepsis are

Indexed as

antibiotic resistanceantimicrobial resistancebacteriophageE. coliESBLKlebsiellaphage therapyurinary tract infection

Identifiers

PMID33868187
PMCPMC8044893
OpenAlexW3150073186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.