Evidence map›Paper›PMID 33868185›Full record

ArticleFrontiers in endocrinology2021

The Impact of COVID-19 Pandemic Lockdown on the Incidence of New-Onset Type 1 Diabetes and Ketoacidosis Among Saudi Children.

Aqeel Alaqeel, Fahad Aljuraibah, Mohammed Alsuhaibani, Mohammed Huneif, Abdulhameed Alsaheel, Mohammad Al Dubayee, Abdulaziz Alsaedi, Ayman Bakkar, Ahmed Alnahari, Areej Taha and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 5 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  11. Type 1 Diabetes and COVID-19: A Literature Review and Possible Management.International journal of endocrinology and metabolism · 2023
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  19. COVID-19 and diabetes in children.Annals of pediatric endocrinology & metabolism · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 1 country.

Aqeel AlaqeelDepartment of Pediatrics, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Fahad AljuraibahPediatric Department, King Abdullah Specialized Children's Hospital, Riyadh, Saudi Arabia.
Mohammed AlsuhaibaniDepartment of Pediatrics, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Mohammed HuneifDepartment of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Abdulhameed AlsaheelPediatric Endocrine Department, Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Mohammad Al DubayeePediatric Department, King Abdullah Specialized Children's Hospital, Riyadh, Saudi Arabia.
Abdulaziz AlsaediAl Hada Armed Forces Hospital, Pediatric Department, Pediatric Endocrine Division, Taif, Saudi Arabia.
Ayman BakkarAl Hada Armed Forces Hospital, Pediatric Department, Pediatric Endocrine Division, Taif, Saudi Arabia.
Ahmed AlnahariDiabetes and Endocrinology Center, King Fahad Central Hospital in Jizan, Jizan, Saudi Arabia.
Areej TahaPediatric Endocrinology Division, Pediatrics Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Khulood AlharbiPediatric Department, King Abdullah Specialized Children's Hospital, Riyadh, Saudi Arabia.
Yousef AlanaziPediatric Department, King Abdullah Specialized Children's Hospital, Riyadh, Saudi Arabia.
Samia AlmadhiPediatric Endocrine Department, Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Reem Al KhalifahPediatric Endocrinology Division, Pediatrics Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Armed Forces Hospital · SAKing Fahd Medical City · SAKing Saud University · SAQassim University · SAKing Abdullah International Medical Research Center · SAKing Fahad Central Hospital · SAKing Saud bin Abdulaziz University for Health Sciences · SAMajmaah University · SANajran University · SATaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Overburdened healthcare systems during the coronavirus disease (COVID-19) pandemic led to suboptimal chronic disease management, including that of pediatric type 1 diabetes mellitus (T1DM). The pandemic also caused delayed detection of new-onset diabetes in children; this increased the risk and severity of diabetic ketoacidosis (DKA). We therefore investigated the frequency of new-onset pediatric T1DM and DKA in Saudi Arabia during the COVID-19 pandemic and compared it to the same period in 2019. Methods: We conducted a multicenter retrospective cohort study, including patients aged 1-14 years admitted with new-onset T1DM or DKA during the COVID-19 pandemic (March-June 2020) and the same period in 2019. We assessed factors including age, sex, anthropometric measures, nationality, duration of diabetes, diabetes management, HbA1c levels, glycemic control, cause of admission, blood gas levels, etiology of DKA, DKA complications, length of hospital stay, and COVID-19 test status. Result: During the lockdown, 106 children, compared with 154 in 2019, were admitted to 6 pediatric diabetes centers. Among the admissions, DKA was higher in 2020 than in 2019 (83% vs. 73%; Conclusion: The lockdown implemented in Saudi Arabia has significantly impacted children with T1DM and led to an increased DKA frequency, including children with new-onset T1DM, potentially owing to delayed presentation.

Indexed as

COVID-19PandemicsAge FactorsAnthropometryBlood Gas AnalysisChildCohort StudiesDiabetes Mellitus, Type 1Diabetic KetoacidosisDisease ManagementFemaleGlycated HemoglobinGlycemic ControlHumansLength of StayMaleGlycated HemoglobinCOVID-19 pandemicDKAlockdownSaudi Arabia (KSA)type 1 diabetes mellitus

Identifiers

PMID33868185
PMCPMC8049603
OpenAlexW3144648158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.