ArticleFrontiers in endocrinology2021
Intermuscular Fat Content in Young Chinese Men With Newly Diagnosed Type 2 Diabetes: Based on MR mDIXON-Quant Quantitative Technique.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 17 citations in OpenAlex.
- Magnetic resonance imaging derived biomarkers for the diagnosis of type 2 diabetes with insulin resistance: A pilot study.World journal of diabetes · 2025Article
- Characteristics of mDIXON-Quant and proton magnetic resonance spectroscopy imaging of thigh skeletal muscles in patients with stroke-related sarcopenia: a prospective case-control study.Journal of Yeungnam medical science · 2025Article
- Compositional and Functional MRI of Skeletal Muscle: A Review.Journal of magnetic resonance imaging : JMRI · 2024Review
- Association between type 2 diabetes mellitus and body composition based on MRI fat fraction mapping.Frontiers in public health · 2024Article
- Mechanisms of body fat distribution and gluteal-femoral fat protection against metabolic disorders.Frontiers in nutrition · 2024Review
- Thigh muscle fat fraction is independently associated with impaired glucose metabolism in individuals with obesity.Endocrine connections · 2023Article
- Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats.Diabetology & metabolic syndrome · 2023Article
- Effects of free weight and body mass-based resistance training on thigh muscle size, strength and intramuscular fat in healthy young and middle-aged individuals.Experimental physiology · 2023Article
- mDIXON-Quant for differentiation of renal damage degree in patients with chronic kidney disease.Frontiers in endocrinology · 2023Article
- The Candidate Schizophrenia Risk GeneFrontiers in endocrinology · 2021Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: Skeletal muscle fat content is one of the important contributors to insulin resistance (IR), but its diagnostic value remains unknown, especially in the Chinese population. Therefore, we aimed to analyze differences in skeletal muscle fat content and various functional MRI parameters between diabetic patients and control subjects to evaluate the early indicators of diabetes. In addition, we aimed to investigate the associations among skeletal muscle fat content, magnetic resonance parameters of skeletal muscle function and IR in type 2 diabetic patients and control subjects. Methods: We enrolled 12 patients (age:29-38 years, BMI: 25-28 kg/m Results: We found a significant difference in intermuscular fat (IMAT) between the diabetes group and the control group ( Conclusion: Deposition of IMAT in skeletal muscles seems to be an important determinant for IR in type 2 diabetes. The skeletal muscle IMAT value greater than 8.85% and the T2 value greater than 39.25ms are suggestive of IR.
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