Evidence map›Paper›PMID 33867970›Full record

ArticleFrontiers in aging neuroscience2021

Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth.

Dennis M Hedderich, Aurore Menegaux, Benita Schmitz-Koep, Rachel Nuttall, Juliana Zimmermann, Sebastian C Schneider, Josef G Bäuml, Marcel Daamen, Henning Boecker, Marko Wilke and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. BrainAGE, brain health, and mental disorders: A systematic review.Neuroscience and biobehavioral reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Dennis M HedderichDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Aurore MenegauxDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Benita Schmitz-KoepDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Rachel NuttallDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Juliana ZimmermannDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Sebastian C SchneiderDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Josef G BäumlTUM-NIC Neuroimaging Center, School of Medicine, Technical University of Munich, Munich, Germany.
Marcel DaamenFunctional Neuroimaging Group, Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Henning BoeckerFunctional Neuroimaging Group, Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Marko WilkeDepartment of Pediatric Neurology and Developmental Medicine and Experimental Pediatric Neuroimaging group, University of Tübingen, Tübingen, Germany.
Claus ZimmerDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Dieter WolkeDepartment of Psychology, University of Warwick, Coventry, United Kingdom.
Peter BartmannDepartment of Neonatology, University Hospital Bonn, Venusberg-Campus, Bonn, Germany.
Christian SorgDepartment of Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
Christian GaserDepartment of Psychiatry, University Hospital Jena, Jena, Germany.
Technical University of Munich · DEUniversity Hospital Bonn · DEJena University Hospital · DEUniversity of Tübingen · DEUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence suggests increased metabolic and physiologic aging rates in premature-born adults. While the lasting consequences of premature birth on human brain development are known, its impact on brain aging remains unclear. We addressed the question of whether premature birth impacts brain age gap estimates (BrainAGE) using an accurate and robust machine-learning framework based on structural MRI in a large cohort of young premature-born adults (

Indexed as

agingbraindevelopmentmagnetic resonance imagingpremature birth

Identifiers

PMID33867970
PMCPMC8047054
OpenAlexW3151738440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.