Evidence map›Paper›PMID 33867950›Full record

ArticleFrontiers in behavioral neuroscience2021

Development of a Classical Conditioning Task for Humans Examining Phasic Heart Rate Responses to Signaled Appetitive Stimuli: A Pilot Study.

Alessandra Sayão, Heloisa Alves, Emi Furukawa, Thomas Schultz Wenk, Mauricio Cagy, Samantha Gutierrez-Arango, Gail Tripp, Egas Caparelli-Dáquer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. The gut and heart's role in reward processing.Frontiers in integrative neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Alessandra SayãoLab of Electric Stimulation of the Nervous System Rio de Janeiro State University, Rio de Janeiro, Brazil.
Heloisa AlvesPsychology Department, University of Massachusetts Dartmouth, North Dartmouth, MA, United States.
Emi FurukawaOkinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Thomas Schultz WenkLab of Electric Stimulation of the Nervous System Rio de Janeiro State University, Rio de Janeiro, Brazil.
Mauricio CagyAlberto Luiz Coimbra Institute for Graduate Studies and Research in Engineering, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Samantha Gutierrez-ArangoMIT Center for Extreme Bionics, Massachusetts Institute of Technology, Cambridge, MA, United States.
Gail TrippOkinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Egas Caparelli-DáquerLab of Electric Stimulation of the Nervous System Rio de Janeiro State University, Rio de Janeiro, Brazil.
Universidade do Estado do Rio de Janeiro · BROkinawa Institute of Science and Technology Graduate University · JPMassachusetts Institute of Technology · USUniversidade Federal do Rio de Janeiro · BRUniversity of Massachusetts Dartmouth · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac responses to appetitive stimuli have been studied as indices of motivational states and attentional processes, the former being associated with cardiac acceleration and latter deceleration. Very few studies have examined heart rate changes in appetitive classical conditioning in humans. The current study describes the development and pilot testing of a classical conditioning task to assess cardiac responses to appetitive stimuli and cues that reliably precede them. Data from 18 adults were examined. They were shown initially neutral visual stimuli (putative CS) on a computer screen followed by pictures of high-caloric food (US). Phasic cardiac deceleration to food images was observed, consistent with an orienting response to motivationally significant stimuli. Similar responses were observed to non-appetitive stimuli when they were preceded by the cue associated with the food images, suggesting that attentional processes were engaged by conditioned stimuli. These autonomic changes provide significant information about classical conditioning effects in humans.

Indexed as

appetitive conditioningattentioncardiac decelerationmotivationorienting response

Identifiers

PMID33867950
PMCPMC8052094
OpenAlexW3141892288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.