ArticleActa stomatologica Croatica2021
Caries Preventive Effects of Theobromine Containing Toothpaste on Early Childhood Caries: Preliminary Results.
Article in Acta stomatologica Croatica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 19 citations in OpenAlex.
- Navigating fluoride hesitancy: mapping the evidence base for fluoride-free toothpaste alternatives.European journal of pediatrics · 2026Review
- The Inhibition of Streptococcus mutans Biofilms following Exposure to Different Chocolate Ingredients.European journal of dentistry · 2026Article
- Effect of a Home Bleaching Gel Containing Chitosan and Theobromine on Tooth Surface Roughness, Microhardness, and Colour Change.Gels (Basel, Switzerland) · 2025Article
- Early Childhood Oral Health Impact Scale: Psychometric Evaluation in Portuguese Preschoolers.Acta stomatologica Croatica · 2024Article
- Theobromine versus casein phospho-peptides/Amorphous calcium phosphate with fluoride as remineralizing agents: effect on resin-dentine bond strength, microhardness, and morphology of dentine.BMC oral health · 2023Article
- Dental Caries Experience in Children in Public Kindergartens of Sarajevo, Bosnia and Herzegovina.Acta stomatologica Croatica · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEnamel remineralizing effects of theobromine have received much attention from the clinicians. The aim of this study was to investigate the caries preventive effect of theobromine containing toothpaste on children with early childhood caries (ECC). MATERIAL AND
methodsSalivary pH, buffering capacity and frequency of
resultsWe included 13 children (mean age 4.25) with 145 teeth in the fluoridated toothpaste (Colgate Kids toothpaste) group; 13 children (mean age 4.46) with 115 teeth in theobromine containing toothpaste (Theodent
conclusionBoth toothpaste group showed a statistically significant amount of enamel remineralization. Since theobromine had the added benefits of increasing the salivary pH and decreasing the
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Registered trials
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