Evidence map›Paper›PMID 33867235›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2021

Outcomes and Risk Factors for Cardiovascular Events in Hospitalized COVID-19 Patients.

Qian Xu, Harideep Samanapally, Pavani Nathala, Vidyulata Salunkhe, Stephen Furmanek, Meredith N Cahill, Trevor McGuffin, Tahboub Mohammad, Bradford Marsili, Jessica Petrey and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Qian XuDepartment of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY.
Harideep SamanapallyDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Pavani NathalaDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Vidyulata SalunkheDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Stephen FurmanekDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Meredith N CahillDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; School of Medicine, University of Louisville, Louisville, KY.
Trevor McGuffinSchool of Nursing, University of Louisville, Louisville, KY.
Tahboub MohammadDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Bradford MarsiliDepartment of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.
Jessica PetreyKornhauser Health Sciences Library, University of Louisville, Louisville, KY.
Ruth CarricoDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Julio RamirezDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.
Ozan AkcaDepartment of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.
Sean P CliffordDepartment of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.
Siddharth PahwaDepartment of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY.
Lynn RoserSchool of Nursing, University of Louisville, Louisville, KY.
Maiying KongDepartment of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY.
Jiapeng HuangDivision of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY; Department of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY. Electronic address: jiapeng.huang@louisville.edu.
Center of Excellence for Research in Infectious Diseases (CERID) Coronavirus Study Group on behalf of the COVID-19 CardioVascular Research Group (COVID-CVRG)
University of Louisville · US

Funding

University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
A Handheld Microchip for GC analysis of breath to screen for COVID-19U18TR003787 · NCATS · UNIVERSITY OF LOUISVILLE · PI FU, XIAO-AN, NANTZ, MICHAEL H · 2021 to 2022
$2.0M
NCATS NIH HHS U18 TR003787NIEHS NIH HHS P30 ES030283
6 · The paper itself

Abstract

objectiveTo analyze outcomes and risk factors of cardiovascular events in a metropolitan coronavirus disease 2019 (COVID-19) database, and to perform a subgroup analysis in African American populations to determine whether outcomes and risk factors are influenced by race.

designRetrospective cohort analysis from March 9, 2020 to June 20, 2020.

settingPopulation-based study in Louisville, KY, USA.

participantsSeven hundred adult inpatients hospitalized with COVID-19.

interventionsN/A. MEASUREMENTS AND MAIN

resultsThis cohort consisted of 126 patients (18%) with cardiovascular events and 574 patients without cardiovascular events. Patients with cardiovascular events had a much higher mortality rate than those without cardiovascular events (45.2% v 8.7%, p < 0.001). There was no difference between African American and white patients regarding mortality (43.9% v 46.3%, p = 1) and length of stay for survivors (11 days v 9.5 days, p = 0.301). Multiple logistics regression analysis suggested that male, race, lower SaO2/F

conclusionsCardiovascular events were prevalent and associated with worse outcomes in hospitalized patients with COVID-19. Outcomes of cardiovascular events in African American and white COVID-19 patients were similar after propensity score matching analysis. There were common and unique risk factors for cardiovascular events in African American COVID-19 patients when compared with white patients.

Indexed as

Cardiovascular DiseasesCOVID-19AdultComorbidityHospitalizationHumansMaleRetrospective StudiesRisk FactorsSARS-CoV-2cardiovascularcoronavirusCOVID-19outcomerisk factorsSARS-CoV-2

Identifiers

PMID33867235
PMCPMC7997853
OpenAlexW3149559525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.